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The more you drink, the harder you fall: A systematic review and meta-analysis of how acute alcohol consumption and injury or collision risk increase together
dc.creator | Taylor, B. | |
dc.creator | Irving, H.M. | |
dc.creator | Kanteres, F. | |
dc.creator | Room, R. | |
dc.creator | Borges, G. | |
dc.creator | Cherpitel, C. | |
dc.creator | Greenfield, T. | |
dc.creator | Rehm, J. | |
dc.date.accessioned | 2017-06-29T06:06:19Z | |
dc.date.available | 2017-06-29T06:06:19Z | |
dc.date.issued | 2010 | es_ES |
dc.identifier | 652 | es_ES |
dc.identifier.issn | 0376-8716 | es_ES |
dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/5336 | |
dc.identifier.uri | https://doi.org/10.1016/j.drugalcdep.2010.02.011 | es_ES |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887748/ | es_ES |
dc.description.abstract | Alcohol consumption causes injury in a dose-response manner. The most common mode of sustaining an alcohol-attributable injury is from a single occasion of acute alcohol consumption, but much of the injury literature employs usual consumption habits to assess risk instead. An analysis of the acute dose-response relationship between alcohol and injury is warranted to generate single occasion- and dose-specific relative risks. A systematic literature review and meta-analysis was conducted to fill this gap. Linear and best-fit first-order model were used to model the data. Usual tests of heterogeneity and publication bias were run. Separate meta-analyses were run for motor vehicle and non-motor vehicle injuries, as well as case-control and case-crossover studies. The risk of injury increases non-linearly with increasing alcohol consumption. For motor vehicle accidents, the odds ratio increases by 1.24 (95% CI: 1.18-1.31) per 10-g in pure alcohol increase to 52.0 (95% CI: 34.50-78.28) at 120g. For non-motor vehicle injury, the OR increases by 1.30(95% CI: 1.26-1.34) to an OR of 24.2 at 140g (95% CI: 16.2-36.2). Case-crossover studies of non-MVA injury result in overall higher risks than case-control studies and the per-drink increase in odds of injury was highest for intentional injury, at 1.38 (95% CI: 1.22-1.55). Efforts to reduce drinking both on an individual level and a population level are important. No level of consumption is safe when driving and less than 2 drinks per occasion should be encouraged to reduce the risk of injury. (c) 2010 Elsevier Ireland Ltd. All rights reserved. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | ELSEVIER IRELAND LTD, ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND | es_ES |
dc.relation | 110 (1-2) 108-116 p. | es_ES |
dc.relation | versión del editor | es_ES |
dc.rights | acceso cerrado | es_ES |
dc.title | The more you drink, the harder you fall: A systematic review and meta-analysis of how acute alcohol consumption and injury or collision risk increase together | es_ES |
dc.type | article | es_ES |
dc.contributor.affiliation | Ctr Addict & Mental Hlth, Toronto, ON M5S 2S1, Canada | es_ES |
dc.contributor.email | bennyjtaylor@gmail.com | es_ES |
dc.relation.jnabreviado | DRUG ALCOHOL DEPEND | es_ES |
dc.relation.journal | Drug and alcohol dependence | es_ES |
dc.identifier.place | Irlanda | es_ES |
dc.date.published | 2010 | es_ES |
dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | es_ES |
dc.identifier.doi | 10.1016/j.drugalcdep.2010.02.011 | es_ES |
dc.description.month | Jul | es_ES |
dc.subject.meshm | Alcohol | es_ES |
dc.subject.meshm | Injury | es_ES |
dc.subject.meshm | Epidemiology | es_ES |
dc.subject.meshm | Risk | es_ES |
dc.subject.meshm | Meta-analysis | es_ES |
dc.subject.ko | CASE-CROSSOVER | es_ES |
dc.subject.ko | EMERGENCY-DEPARTMENT | es_ES |
dc.subject.ko | MOTORCYCLE CRASHES | es_ES |
dc.subject.ko | FATAL INJURIES | es_ES |
dc.subject.ko | GLOBAL BURDEN | es_ES |
dc.subject.ko | POPULATION | es_ES |
dc.subject.ko | PERCEPTION | es_ES |
dc.subject.ko | DRIVERS | es_ES |
dc.subject.ko | DISEASE | es_ES |
dc.subject.ko | ADULTS | es_ES |
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