2025-11-112026-03-272025-11-1120140185-332510.17711/SM.0185-3325.2014.059https://doi.org/10.17711/SM.0185-3325.2014.059https://repositorio.inprf.gob.mx/handle/123456789/8497Introduction One of the most researched theories of personality is the Five Factor Model, frequently evaluated through the Big Five Inventory. Even though there is a Spanish version, its psychometrical properties in Mexican population are yet unknown. Methods. We evaluated 472 adults (217 male/255 female) from an open population from Mexico City. Results. We obtained a total scale reliability score of α=0.72. Principal Component Analysis using Velicer’s Minimun Average Partial validated a 5 factor structure. We also found differences between subjects that had been diagnosed with a psychiatric or neurological disorder by a health professional in agreeableness, responsability and neuroticism. Conclusions. Our results suggest that the Big Five Inventory is useful to evaluate the personality in Mexican population. However, a review of the Agreeableness scale may be needed because its low reliability and poor item loadings.PDFengAcceso AbiertoArtículo0186-761XInstituto Nacional de Psiquiatría Ramón de la Fuente MuñizMéxicoBig Five Inventory ConstructValidity