2017-06-292026-03-272017-06-292016Elizabeth Cuesta Hernández0165-572810.1016/j.jneuroim.2015.11.011http://dx.doi.org/10.1016/j.jneuroim.2015.11.011https://repositorio.inprf.gob.mx/handle/123456789/4609Fibromyalgia (FM)is a chronic disease that has been linked to inflammatory reactions and changes in the systemic levels of proinflammatory cytokines that modulate responses in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. We found that concentrations of IL-6 and IL-8were elevated in FM patients. Both cytokines correlated with clinical scores, suggesting that IL-6 and IL-8 have additive or synergistic effects in perpetuating the chronic pain in FM patients. These findings indicate that IL-6 and IL-8 are two of the most constant inflammatory mediators in FM and that their levels correlate significantly with the severity of symptomsengAcceso CerradoArtículo1872-8421Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz22-25Países Bajos290FibromyalgiaIL-6IL-8FIQInflammation