Alterations on the morphology, nitric oxide synthesis and activity of platelets reproduced in rats as possible biomarkers for depression are reversed by fluoxetine

2017-06-302026-03-272017-06-302012Tomás Martínez Ibarra0091-305710.1016/j.pbb.2012.03.012https://doi.org/10.1016/j.pbb.2012.03.012https://repositorio.inprf.gob.mx/handle/123456789/6809engacceso cerradoAlterations on the morphology, nitric oxide synthesis and activity of platelets reproduced in rats as possible biomarkers for depression are reversed by fluoxetinearticle1873-51772Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México.349-356Tarrytown, NY102DepressionFluoxetineForced swimming testMorphologyNitric oxidePlateletsSerotoninDepresiónFluoxetinaPrueba forzada de nataciónMorfologíaOxido nítricoPlaquetasSerotoninaAnimalsBehavior, Animal-Drug effectsBiological Markers-BloodBlood Platelets-Drug effectsBlood Platelets-MetabolismBlood Platelets-UltrastructureDepression-BloodDepression-Drug therapyFluoxetine-PharmacologyFluoxetine-Therapeutic useMaleMembrane PotentialsNitric Oxide-BiosynthesisRatsRats, WistarSerotonin-BloodSerotonin Uptake Inhibitors-PharmacologySerotonin Uptake Inhibitors-Therapeutic useTryptophan-Blood