IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients

dc.contributor.affiliationClinical Service, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexicoes_ES
dc.contributor.emaildanemend@hotmail.com, cruza_dl@hotmail.com, maribel_barrerav@yahoo.com.mxes_ES
dc.creatorMendieta, Danelia
dc.creatorDe la Cruz-Aguilera, Dora Luz
dc.creatorBarrera-Villalpando, Maria Isabel
dc.creatorBecerril-Villanueva, Enrique
dc.creatorArreola, Rodrigo
dc.creatorHernández-Ferreira, Erick
dc.creatorPérez-Tapia, Sonia Mayra
dc.creatorPérez-Sánchez, Gilberto
dc.creatorGarcés-Alvarez, María Eugenia
dc.creatorAguirre-Cruz, Lucinda
dc.creatorVelasco-Velázquez, Marco Antonio
dc.creatorPavón, Lenin
dc.creator.identificador"http://orcid.org/0000-0002-4280-0570">Aguirre Cruz, Lucindaes_ES
dc.creator.identificador"CUAD560921MCLRGR02">De la Cruz Aguilera, Dora Luzes_ES
dc.date.accessioned2017-06-29T03:53:19Z
dc.date.accessioned2026-03-27T14:33:07Z
dc.date.available2017-06-29T03:53:19Z
dc.date.issued2016es_ES
dc.date.published2016es_ES
dc.descriptionFibromyalgia (FM)is a chronic disease that has been linked to inflammatory reactions and changes in the systemic levels of proinflammatory cytokines that modulate responses in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. We found that concentrations of IL-6 and IL-8were elevated in FM patients. Both cytokines correlated with clinical scores, suggesting that IL-6 and IL-8 have additive or synergistic effects in perpetuating the chronic pain in FM patients. These findings indicate that IL-6 and IL-8 are two of the most constant inflammatory mediators in FM and that their levels correlate significantly with the severity of symptoms
dc.identifier2760es_ES
dc.identifier.citationElizabeth Cuesta Hernándezes_ES
dc.identifier.doi10.1016/j.jneuroim.2015.11.011es_ES
dc.identifier.eissn1872-8421es_ES
dc.identifier.issn0165-5728es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.paginacion22-25es_ES
dc.identifier.placePaíses Bajoses_ES
dc.identifier.urihttp://dx.doi.org/10.1016/j.jneuroim.2015.11.011es_ES
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/4609
dc.identifier.volumen290es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation290:22-25es_ES
dc.relation.jnabreviadoJ NEUROIMMUNOLes_ES
dc.relation.journalJournal of Neuroimmunologyes_ES
dc.rightsAcceso Cerradoes_ES
dc.subject.kwFibromyalgia
dc.subject.kwIL-6
dc.subject.kwIL-8
dc.subject.kwFIQ
dc.subject.kwInflammation
dc.titleIL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patientses_ES
dc.typeArtículoes_ES

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