IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients
| dc.contributor.affiliation | Clinical Service, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexico | es_ES |
| dc.contributor.email | danemend@hotmail.com, cruza_dl@hotmail.com, maribel_barrerav@yahoo.com.mx | es_ES |
| dc.creator | Mendieta, Danelia | |
| dc.creator | De la Cruz-Aguilera, Dora Luz | |
| dc.creator | Barrera-Villalpando, Maria Isabel | |
| dc.creator | Becerril-Villanueva, Enrique | |
| dc.creator | Arreola, Rodrigo | |
| dc.creator | Hernández-Ferreira, Erick | |
| dc.creator | Pérez-Tapia, Sonia Mayra | |
| dc.creator | Pérez-Sánchez, Gilberto | |
| dc.creator | Garcés-Alvarez, María Eugenia | |
| dc.creator | Aguirre-Cruz, Lucinda | |
| dc.creator | Velasco-Velázquez, Marco Antonio | |
| dc.creator | Pavón, Lenin | |
| dc.creator.identificador | "http://orcid.org/0000-0002-4280-0570">Aguirre Cruz, Lucinda | es_ES |
| dc.creator.identificador | "CUAD560921MCLRGR02">De la Cruz Aguilera, Dora Luz | es_ES |
| dc.date.accessioned | 2017-06-29T03:53:19Z | |
| dc.date.accessioned | 2026-03-27T14:33:07Z | |
| dc.date.available | 2017-06-29T03:53:19Z | |
| dc.date.issued | 2016 | es_ES |
| dc.date.published | 2016 | es_ES |
| dc.description | Fibromyalgia (FM)is a chronic disease that has been linked to inflammatory reactions and changes in the systemic levels of proinflammatory cytokines that modulate responses in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. We found that concentrations of IL-6 and IL-8were elevated in FM patients. Both cytokines correlated with clinical scores, suggesting that IL-6 and IL-8 have additive or synergistic effects in perpetuating the chronic pain in FM patients. These findings indicate that IL-6 and IL-8 are two of the most constant inflammatory mediators in FM and that their levels correlate significantly with the severity of symptoms | |
| dc.identifier | 2760 | es_ES |
| dc.identifier.citation | Elizabeth Cuesta Hernández | es_ES |
| dc.identifier.doi | 10.1016/j.jneuroim.2015.11.011 | es_ES |
| dc.identifier.eissn | 1872-8421 | es_ES |
| dc.identifier.issn | 0165-5728 | es_ES |
| dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | es_ES |
| dc.identifier.paginacion | 22-25 | es_ES |
| dc.identifier.place | Países Bajos | es_ES |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.jneuroim.2015.11.011 | es_ES |
| dc.identifier.uri | https://repositorio.inprf.gob.mx/handle/123456789/4609 | |
| dc.identifier.volumen | 290 | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Elsevier | es_ES |
| dc.relation | 290:22-25 | es_ES |
| dc.relation.jnabreviado | J NEUROIMMUNOL | es_ES |
| dc.relation.journal | Journal of Neuroimmunology | es_ES |
| dc.rights | Acceso Cerrado | es_ES |
| dc.subject.kw | Fibromyalgia | |
| dc.subject.kw | IL-6 | |
| dc.subject.kw | IL-8 | |
| dc.subject.kw | FIQ | |
| dc.subject.kw | Inflammation | |
| dc.title | IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients | es_ES |
| dc.type | Artículo | es_ES |
