Mirtazapine decreased cocaine-induced c-fos expression and dopamine release in rats

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dc.contributor.affiliationSubdirección de Investigaciones Clínicas, Laboratorio de Neurofarmacología Conductual, Microcirugía y Terapéutica Experimental, Instituto Nacional de Psiquiatría, Ciudad de México, México
dc.contributor.emailazazel_vamp@yahoo.com.mx
dc.creatorBarbosa-Méndez, Susana
dc.creatorSalazar-Juárez, Alberto
dc.date2024
dc.date.accessioned2026-06-03T17:29:56Z
dc.date.issued2024
dc.date.published2024
dc.descriptionChronic cocaine exposure induces an increase in dopamine release and an increase in the expression of the Fos protein in the rat striatum. It has been suggested that both are necessary for the expression of cocaine-induced alterations in behavior and neural circuitry. Mirtazapine dosing attenuated the cocaine-induced psychomotor and reinforcer effects.
dc.formatPDF
dc.identifierOE02IC2025
dc.identifier.doi10.3389/fpsyt.2024.1428730
dc.identifier.issn1664-0640
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.placeSuiza
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/47
dc.identifier.urihttps://doi.org/10.3389/fpsyt.2024.1428730
dc.language.isoeng
dc.publisherFrontiers Research Foundation
dc.relation15:1428730
dc.relation.jnabreviadoFRONT PSYCHIATRY
dc.relation.journalFrontiers in Psychiatry
dc.rightsAcceso Cerrado
dc.subject.kwCocaine
dc.subject.kwLocomotor activity
dc.subject.kwLocomotor sensitization
dc.subject.kwMirtazapine
dc.subject.kwMulti-target drugs
dc.titleMirtazapine decreased cocaine-induced c-fos expression and dopamine release in rats
dc.typeArtículo

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