Prenatal and postnatal cocaine exposure enhances the anxiety- and depressive-like behaviors in rats: An ontogenetic study

Simple item page
dc.contributor.affiliationSubdireccion de Investigaciones Clínicas, Laboratorio de Neurofarmacología Conductual, Microcirugía y Terapéutica Experimental, Instituto Nacional de Psiquiatría, Mexico City 14370, Mexico.
dc.contributor.emailazazel_vamp@yahoo.com.mx
dc.creatorBarbosa Méndez, Susana
dc.creatorSalazar-Juárez, Alberto
dc.date2024
dc.date.accessioned2026-07-01T19:41:50Z
dc.date.issued2024
dc.date.published2024
dc.descriptionPrenatal and postnatal exposure to drugs such as cocaine is a public health problem that causes deficits in brain development and function in humans and animals. One of the main effects of prenatal and postnatal cocaine exposure is increased vulnerability to developing the substance use disorder at an early age. Furthermore, the negative emotional states associated with cocaine withdrawal increase the fragility of patients to relapse into drug abuse. In this sense, prenatal and postnatal cocaine exposure enhanced the cocaine- and nicotine-induced locomotor activity and locomotor sensitization, and rats exposed prenatally to cocaine displayed an increase in anxiety- and depressive-like behaviors in adulthood (PND 60-70).
dc.formatPDF
dc.identifierOE30IC2025
dc.identifier.doi10.1002/jdn.10358
dc.identifier.eissn1873-474X
dc.identifier.issn0736-5748
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.placeEstados Unidos
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/164
dc.identifier.urihttps://doi.org/10.1002/jdn.10358
dc.language.isoeng
dc.publisherWiley
dc.relation84(6):546-557
dc.relation.jnabreviadoINT J DEV NEUROSCI
dc.relation.journalInternational Journal of Developmental Neuroscience
dc.rightsAcceso Cerrado
dc.subject.kwAnxiety‐like behavior
dc.subject.kwCocaine
dc.subject.kwCocaine withdrawal
dc.subject.kwDepressive‐like behavior
dc.subject.kwPrenatal drug exposure
dc.titlePrenatal and postnatal cocaine exposure enhances the anxiety- and depressive-like behaviors in rats: An ontogenetic study
dc.typeArticulo

Files

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Artículos de revista