Epigenetic factors and ncRNAs in testicular cancer

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dc.contributor.affiliationPosgrado en Ciencias Genómicas, Universidad Autónoma De México (UACM), San Lorenzo 290, Col. Del Valle, México City 03100, Mexico
dc.contributor.emailmaria.alvarez@uacm.edu.mx
dc.creatorNuñez-Corona, Davides_ES
dc.creatorContreras-Sanzón, Estefaniaes_ES
dc.creatorPuente-Rivera, Jonathanes_ES
dc.creatorArreola, Rodrigoes_ES
dc.creatorCamacho-Nuez, Minervaes_ES
dc.creatorSantiago, José Cruzes_ES
dc.creatorEstrella-Parra, Edgar Antonioes_ES
dc.creatorTorres-Romero, Julio Césares_ES
dc.creatorLópez-Camarillo, Césares_ES
dc.creatorAlvarez-Sánchez, María Elizbethes_ES
dc.creator.identificadorhttps://orcid.org/0000-0001-6941-6248 (Puente-Rivera, Jonathan)
dc.creator.identificadorhttps://orcid.org/0000-0003-2417-418X (Arreola, Rodrigo)
dc.creator.identificadorhttps://orcid.org/0000-0002-0417-0969 (Torres-Romero, Julio César)
dc.creator.identificadorhttps://orcid.org/0000-0002-9417-2609 (López-Camarillo, César)
dc.date2023
dc.date.accessioned2025-03-11T16:18:05Z
dc.date.accessioned2026-03-27T15:31:15Z
dc.date.available2025-03-11T16:18:05Z
dc.date.issued2023
dc.date.published2023
dc.descriptionTesticular cancer is the most prevalent tumor among males aged 15 to 35, resulting in a significant number of newly diagnosed cases and fatalities annually. Non-coding RNAs (ncRNAs) have emerged as key regulators in various cellular processes and pathologies, including testicular cancer. Their involvement in gene regulation, coding, decoding, and overall gene expression control suggests their potential as targets for alternative treatment approaches for this type of cancer. Furthermore, epigenetic modifications, such as histone modifications, DNA methylation, and the regulation by microRNA (miRNA), have been implicated in testicular tumor progression and treatment response. Epigenetics may also offer critical insights for prognostic evaluation and targeted therapies in patients with testicular germ cell tumors (TGCT). This comprehensive review aims to present the latest discoveries regarding the involvement of some proteins and ncRNAs, mainly miRNAs and lncRNA, in the epigenetic aspect of testicular cancer, emphasizing their relevance in pathogenesis and their potential, given the fact that their specific expression holds promise for prognostic evaluation and targeted therapies.es_ES
dc.formatPDFes_ES
dc.identifierJC05IC23es_ES
dc.identifier.doi10.3390/ijms241512194
dc.identifier.eissn1422-0067
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.placeSuiza
dc.identifier.urihttps://doi.org/10.3390/ijms241512194
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/8237
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relation24(15):12194
dc.relation.jnabreviadoINT J MOL SCI
dc.relation.journalInternational Journal of Molecular Sciences
dc.rightsAcceso Cerradoes_ES
dc.titleEpigenetic factors and ncRNAs in testicular canceres_ES
dc.typeArtículoes_ES

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