The effect of triazolam on insomniac patients using a laboratory sleep evaluation

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dc.contributor.affiliationUnidad de Investigaciones Cerebrales, Instituto Nacional de Neurología y Neurocirugía and Facultad de Psicología, UNAM, México, D.F.es_ES
dc.creatorFernández-Guardiola, Augusto
dc.creatorJurado, José Luis
dc.creator.identificador"FEGA210324HNERRG05">Fernández Guardiola, Augustoes_ES
dc.date.accessioned2017-06-29T04:13:11Z
dc.date.accessioned2026-03-27T14:33:27Z
dc.date.available2017-06-29T04:13:11Z
dc.date.issued1981es_ES
dc.date.published1981es_ES
dc.description.abstractotrodiomaPrevious reports have demonstrated various degrees of hypnotic effectiveness of triazolam. Most of these, however, used subjective patient or physician evaluation and many were single dose. Consequently, this study was undertaken. Eight subjects were polygraphically recorded during 7 nightly hours in various experimental situations, under double-blind cross-over study design, in order to analyze the effects of 0.25 and 0.50 mg triazolam. Each subject was subjected to two habituation nights followed by one control night and then received either dose during 5 consecutive days, with a one-week interval between both as a washout period. The fourth and fifth night of each period were studied. Only the latter was evaluated. The results showed that the 0.5-mg dose produced a significant increase in the total sleep time, a significant increase in phase 2 and a significant decrease in the number of nightly movements. The 0.25-mg dose caused a significant decrease in the number of awakenings, and both doses brought a significant decrease in the REM phase. The side effects found included a slight motor incoordination during the treatment, more pronounced with the higher dose. These results on the polysomnogram are similar to the ones produced by tricyclic antidepressants and other benzodiazepines.es_ES
dc.description.monthJunes_ES
dc.identifier9es_ES
dc.identifier.citationJuan Carlos Bautista Ramírezes_ES
dc.identifier.issn0011-393Xes_ES
dc.identifier.numero6es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.paginacion950-958es_ES
dc.identifier.placeNew Yorkes_ES
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/4707
dc.identifier.volumen29es_ES
dc.language.isoenges_ES
dc.relation29 (6) 950-958 p.es_ES
dc.relationversión del editores_ES
dc.relation.jnabreviadoCURR THER RESes_ES
dc.relation.journalCurrent Therapeutic Researches_ES
dc.rightsacceso cerradoes_ES
dc.titleThe effect of triazolam on insomniac patients using a laboratory sleep evaluationes_ES
dc.typearticlees_ES

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