How inflammation influences psychiatric disease

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dc.contributor.affiliationDivisión de Investigación Clínica de la Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico
dc.contributor.emaillkuriaki@inprf.gob.mx (Lenin Pavón)
dc.creatorFerat-Osorio, Eduardo
dc.creatorMaldonado-García, José Luis
dc.creatorPavón, Lenin
dc.date2024
dc.date.accessioned2026-06-22T20:00:05Z
dc.date.issued2024
dc.date.published2024
dc.descriptionRecent studies highlight the strong correlation between infectious diseases and the development of neuropsychiatric disorders. In this editorial, we comment on the article "Anti-infective therapy durations predict psychological stress and laparoscopic surgery quality in pelvic abscess patients" by Zhang et al, published in the recent issue of the World Journal of Psychiatry 2023; 13 (11): 903-911. Our discussion highlighted the potential consequences of anxiety, depression, and psychosis, which are all linked to bacterial, fungal, and viral infections, which are relevant to the impact of inflammation on the sequelae in mental health as those we are observing after the coronavirus disease 2019 pandemic. We focus specifically on the immune mechanisms triggered by inflammation, the primary contributor to psychiatric complications. Importantly, pathophysiological mechanisms such as organ damage, post-injury inflammation, and infection-induced endocrine alterations, including hypocortisolism or autoantibody formation, significantly contribute to the development of chronic low-grade inflammation, promoting the emergence or development of psychiatric alterations in susceptible individuals. As inflammation can have long-term effects on patients, a multidisciplinary treatment plan can avoid complications and debilitating health issues, and it is crucial to recognize and address the mental health implications.
dc.formatPDF
dc.identifierJC25NC24
dc.identifier.doi10.5498/wjp.v14.i3.342
dc.identifier.eissn2220-3206
dc.identifier.placeEstados Unidos
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/130
dc.identifier.urihttps://dx.doi.org/10.5498/wjp.v14.i3.342
dc.language.isoeng
dc.publisherBaishideng Publishing Group
dc.relation14(3):342-349
dc.relation.jnabreviadoWORLD J PSYCHIATRY
dc.relation.journalWorld Journal of Psychiatry
dc.rightsAcceso Cerrado
dc.subject.kwInflammation
dc.subject.kwInfection
dc.subject.kwDepression
dc.subject.kwPelvic inflammatory disease
dc.subject.kwPsychiatric complication
dc.titleHow inflammation influences psychiatric disease
dc.typeArtículo

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