Immunomodulation and anti-inflammatory effects of garlic compounds

Simple item page
dc.contributor.affiliationPsychiatric Genetics Department, National Institute of Psychiatry, "Ramón de la Fuente", Clinical Research Branch, Calzada México-Xochimilco 101, Colonia San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexico
dc.contributor.emaillahunsotz@yahoo.com.mx(Rodrigo Arreola) daniel.ortuno.sahagun@gmail.com (Daniel Ortuño-Sahagún)
dc.creatorArreola, Rodrigoes_ES
dc.creatorQuintero-Fabián, Sarayes_ES
dc.creatorLópez-Roa, Rocío Ivettees_ES
dc.creatorFlores-Gutiérrez, Enrique Octavioes_ES
dc.creatorReyes-Grajeda, Juan Pabloes_ES
dc.creatorCarrera-Quintanar, Lucreciaes_ES
dc.creatorOrtuño-Sahagún, Danieles_ES
dc.date2015
dc.date.accessioned2025-10-21T18:35:33Z
dc.date.accessioned2026-03-27T15:33:20Z
dc.date.available2025-10-21T18:35:33Z
dc.date.issued2015
dc.date.published2015
dc.descriptionThe benefits of garlic to health have been proclaimed for centuries; however, only recently have Allium sativum and its derivatives been proposed as promising candidates for maintaining the homeostasis of the immune system. The complex biochemistry of garlic makes it possible for variations in processing to yield different preparations with differences in final composition and compound proportion. In this review, we assess the most recent experimental results, which indicate that garlic appears to enhance the functioning of the immune system by stimulating certain cell types, such as macrophages, lymphocytes, natural killer (NK) cells, dendritic cells, and eosinophils, by mechanisms including modulation of cytokine secretion, immunoglobulin production, phagocytosis, and macrophage activation. Finally, because immune dysfunction plays an important role in the development and progress of several diseases, we critically examined immunoregulation by garlic extracts and compounds isolated, which can contribute to the treatment and prevention of pathologies such as obesity, metabolic syndrome, cardiovascular disorders, gastric ulcer, and even cancer. We concluded that A. sativum modulates cytokine secretion and that such modulation may provide a mechanism of action for many of their therapeutic effects.es_ES
dc.formatPDFes_ES
dc.identifier.doi10.1155/2015/401630
dc.identifier.eissn2314-7156
dc.identifier.issn2314-8861
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.placeEgipto
dc.identifier.urihttps://doi.org/10.1155/2015/401630
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/8469
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.relation2015:401630
dc.relation.jnabreviadoJ IMMUNOL RES
dc.relation.journalJournal of Immunology Research
dc.rightsAcceso Cerradoes_ES
dc.titleImmunomodulation and anti-inflammatory effects of garlic compoundses_ES
dc.typeArtículoes_ES

Files

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Plain Text
Description:
Download

Collections

Artículos de revista