Habituation and dehabituation of the spinal polysynaptic reflex responses: modification by naloxone and opiates and their anatomical correlates

dc.contributor.affiliationInstituto Mexicano de Psiquiatría, División de Investigaciones en Neurociencias.es_ES
dc.creatorFernández Guardiola A.
dc.creatorPellicer F.
dc.creatorLeón Olea M.
dc.creatorAsai M.
dc.creatorSánchez Alvarez M.
dc.creator.identificador"AACM530521HDFSMG07">Asai Camacho, Migueles_ES
dc.creator.identificador"FEGA210324HNERRG05">Fernández Guardiola, Augustoes_ES
dc.creator.identificador"LEOM521022MDFNLR08">León Olea, Marthaes_ES
dc.date.accessioned2017-06-29T03:51:58Z
dc.date.accessioned2026-03-27T14:33:04Z
dc.date.available2017-06-29T03:51:58Z
dc.date.issued1989es_ES
dc.date.published1989es_ES
dc.description.abstractotrodiomaThe sustained inhibitory action of spinal endorphins could be responsible for the habituation of polysynaptic responses in the spinal cord. To test this hypothesis, acute spinalized unanesthetized cats (decerebrated and curarized) were used. Sural nerve electrical stimulation (0.2Hz) was provided and a progressive decrease in the reflex response was found. Conversely, the field potential (lamina V) progressively increased during stimulation, reaching its maximum amplitude when ventral root response dehabituation or prevented habituation. The immunohistological results showed leu-enkephalin-like immunoreactive dot-like structures in close proximity to neurons of lamine VII. VIII and IX in the lumbo-sacral segment of the spinal cord. Our results suggest an involvement of opioid peptides in the habituation process.es_ES
dc.description.monthAgo-Sepes_ES
dc.identifier2743es_ES
dc.identifier.citationJuan Carlos Bautista Ramírezes_ES
dc.identifier.doi10.1016/0143-4179(89)90068-1es_ES
dc.identifier.eissn1532-2785es_ES
dc.identifier.issn0143-4179es_ES
dc.identifier.numero2es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.paginacion115-120es_ES
dc.identifier.placePaíses Bajoses_ES
dc.identifier.urihttps://repositorio.inprf.gob.mx/handle/123456789/4592
dc.identifier.volumen14es_ES
dc.language.isoenges_ES
dc.publisherAmsterdam : Elsevieres_ES
dc.relation14 (2) 115-120 p.es_ES
dc.relationversión del editores_ES
dc.relation.jnabreviadoNEUROPEPTIDESes_ES
dc.relation.journalNeuropeptideses_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAnimalses_ES
dc.subject.meshCatses_ES
dc.subject.meshDecerebrate Statees_ES
dc.subject.meshElectric Stimulationes_ES
dc.subject.meshEnkephalin, Leucine/analysises_ES
dc.subject.meshEnkephalins/pharmacologyes_ES
dc.subject.meshEvoked Potentialses_ES
dc.subject.meshHabituation, Psychophysiologic/drug effectses_ES
dc.subject.meshImmunoenzyme Techniqueses_ES
dc.subject.meshNaloxone/pharmacologyes_ES
dc.subject.meshReflex/drug effectses_ES
dc.subject.meshSpinal Cord/analysises_ES
dc.subject.meshSpinal Cord/physiologyes_ES
dc.subject.meshVagotomyes_ES
dc.titleHabituation and dehabituation of the spinal polysynaptic reflex responses: modification by naloxone and opiates and their anatomical correlateses_ES
dc.typeartículoes_ES

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