Artículos de revista

Permanent URI for this collectionhttps://repositorio.inprf.gob.mx/handle/123456789/5

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Author: search.filters.author.Benítez-King, GloriaSubject: search.filters.subject.Melatonin

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    Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression
    (Wiley, 2018) Valdés-Tovar, Marcela; Estrada-Reyes, Rosa; Solís-Chagoyán, Héctor; Argueta, Jesús; Dorantes-Barrón, Ana María; Quero-Chávez, Daniel; Cruz-Garduño, Ricardo; Cercós, Montserrat G.; Trueta, Citlali; Oikawa-Sala, Julián; Dubocovich, Margarita L.; Benítez-King, Gloria; Laboratorio de Neurofarmacología, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico; bekin@imp.edu.mx ( Gloria Benítez-King)
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    The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice
    (MDPI, 2018) Estrada-Reyes, Rosa; Valdés-Tovar, Marcela; Arrieta-Baez, Daniel; Dorantes-Barrón, Ana María; Quero-Chávez, Daniel; Solís-Chagoyán, Héctor; Argueta, Jesús; Dubocovich, Margarita L.; Benítez-King, Gloria; Laboratorio de Fitofarmacología, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico; bekin@imp.edu.mx
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    Olfactory neuronal precursors as a model to analyze the effects of melatonin in Alzheimer's disease.
    (ST BIo-Life, 2023) Santillán-Morales, Valeria; Benítez-King, Gloria; Laboratorio de Neurofarmacología, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, Mexico City 14370, Mexico.; bekin54@hotmail.com
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    Melatonin: a neurotrophic factor?
    (MDPI, 2022) Miranda-Riestra, Armida; Estrada-Reyes, Rosa; Torres-Sanchez, Erandis D.; Carreño-García, Silvia; Gabriel Ortiz, Genaro; Benítez-King, Gloria; Laboratorio de Neurofarmacología, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan 14370, Mexico City, Mexico; genarogabriel@yahoo.com (G.G.O.) ; bekin@imp.edu.mx (G.B.-K.)
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    Further evidence of the melatonin calmodulin interaction: effect on CaMKII activity
    (MDPI, 2022) Argueta, Jesús; Solís-Chagoyán, Héctor; Estrada-Reyes, Rosa; Constantino-Jonapa, Luis A.; Oikawa-Sala, Julián; Velázquez-Moctezuma, Javier; Benítez-King, Gloria; Laboratorio de Neurofarmacología, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, Mexico City 14370, Mexico; bekin@imp.edu.mx, bekin54@hotmail.com ( Gloria Benítez-King)
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    Low doses of ketamine and melatonin in combination produce additive antidepressant-like effects in mice
    (MDPI, 2021) Estrada-Reyes, Rosa; Quero-Chávez, Daniel B.; Trueta, Citlali; Miranda, Armida; Valdés-Tovar, Marcela; Alarcón-Elizalde, Salvador; Oikawa-Sala, Julián; Argueta, Jesús; Constantino-Jonapa, Luis A.; Muñoz-Estrada, Jesús; Dubocovich, Margarita L.; Benítez-King, Gloria; Laboratorio de Fitofarmacología, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.; bekin@imp.edu.mx; bekin54@hotmail.com (Benítez-King, Gloria)
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    Melatonin rescues the dendrite collapse induced by the pro-oxidant toxin okadaic acid in organotypic cultures of rat hilar hippocampus
    (2020) Solís-Chagoyán, Héctor; Domínguez-Alonso, Aline; Valdés-Tovar, Marcela; Argueta, Jesús; Sánchez-Florentino, Zulay A.; Calixto, Eduardo; Benítez-King, Gloria; Laboratorio de Neurofarmacología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City 14370, Mexico.; bekin@imp.edu.mx
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    Melatonin supplementation delays the decline of adult hippocampal neurogenesis during normal aging of mice
    (ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2012) Ramírez-Rodríguez, Gerardo; Vega-Rivera, Nelly M.; Benítez-King, Gloria; Castro-García, Mario; Ortíz-López, Leonardo; Laboratory of Neurogenesis, Division of Clinical Research, National Institute of Psychiatry, México, D.F., Mexico; gbernabe@imp.edu.mx
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    ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration
    (2009) Ortíz-López, Leonardo; Morales-Mulia, Sandra; Ramírez-Rodríguez, Gerardo; Benítez-King, Gloria
    Cell movement is generated by a driving force provided by dynamic cytoskeletal organization. Two main cytoskeletal-dependent features, essential for migration, are the highly cell polarized structure and focal adhesion complexes. Cell migration and substrate anchorage are finely regulated by external signaling exerted by growth factors and hormones. In particular, the serine threonine kinase activated by the small GTPase Rho, the Rho-associated protein kinase (ROCK), participate in both processes through regulation of actin rearrangements in lamellipodia, filopodia, ruffles, and stress fibers. Melatonin, the main product secreted by the pineal gland has oncostatic properties. In MCF-7 cells, 1 nm melatonin reduces migration and invasiveness through increased expression of two cell surface adhesion proteins, E-cadherin and _1-integrin. In this work, we studied the microfilament and microtubule rearrangements elicited by melatonin in migrating leader MCF-7 cells by a wound-healing assay. Additionally, cell anchorage was estimated by quantification of focal adhesions in MCF-7 cells cultured with melatonin. ROCK participation in the indole effects on anchorage and migration was explored by inhibition of the kinase activity with the specific inhibitor of ROCK, the Y-27632 compound. The results indicate that ROCK participates in the melatonin inhibitory effects on cell migration by changing cytoskeletal organization of leader MCF-7 cells. Also, they indicated that indole increased the number of focal contacts through ROCK. These results support the notion that melatonin inhibits cancer cell invasion and metastasis formation via ROCK-regulated microfilament and microtubule organization that converge in a migration/anchorage switch.
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    Haloperidol causes cytoskeletal collapse in N1E-115 cells through tau hyperphosphorylation induced by oxidative stress: Implications for neurodevelopment
    (ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2010) Benítez-King, Gloria; Ortíz-López, Leonardo; Jiménez-Rubio, Graciela; Ramírez-Rodríguez, Gerardo; Departamento de Neurofarmacología, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México, D.F., México; bekin@imp.edu.mx