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  1. Home
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Browsing by Author "Cruz, Silvia L."

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    Cardiovascular effects of different schedules of nicotine administration on spinal rats: influence of pentobarbital
    (1994) Cruz, Silvia L.; Fernández-Guasti, Alonso; Sección de Terapéutica Experimental, Departamento de Farmacología, CINVESTAV, IPN, Mexico, D.F.
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    Challenges to Neuroscience and Public Policy Derived from New Trends and Patterns of Inhalant Misuse
    (Editorial Board, 2014) Medina-Mora, María Elena; Villatoro, Jorge A.; Fleiz, Clara; Domínguez, Mario; Cruz, Silvia L.; National Institute of Psychiatry “Ramon de la Fuente Muniz,” Calzada M´exico Xochimilco 101 Colonia San Lorenzo Huipulco, 14370 Mexico, DF, Mexico; medinam@imp.edu.mx
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    Exposure to toluene and stress during pregnancy impairs pups' growth and dams' lactation 
    (Pergamon-Elsevier Science LTD, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England, 2013) Soberanes-Chavez, Paulina; Lopez-Rubalcava, Carolina; de Gortari, Patricia; Cruz, Silvia L.; https://doi.org/10.1016/j.ntt.2013.07.011; CINVESTAV, Dept Farmacobiol, Calzada Tenorios 235, Mexico City 14330, DF, Mexico; slcruz@cinvestav.mx 
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    Fentanyl is used in Mexico's northern border: current challenges for drug health policies
    (Wiley-Blackwell, 2020) Fleiz, Clara; Arredondo, Jaime; Chavez, Alfonso; Pacheco, Lilia; Segovia, Luis A.; Villatoro, Jorge A.; Cruz, Silvia L.; Medina-Mora, María E.; Fuente, Juan R. de la; National Institute of Psychiatry, Ramon de la Fuente Muñiz (INPRM), Mexico City, Mexico.; fleiz@imp.edu.mx
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    Misusing volatile substances for their hallucinatory effects: A qualitative pilot study with Mexican teenagers and a pharmacological discussion of their hallucinations
    (2011) Cruz, Silvia L.; Domínguez, Mario; Dirección de Investigaciones Epidemiológicas y Psicosociales. Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
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    Misusing Volatile Substances for Their hallucinatory Effects: A Qualitative Pilot Study With Mexican Teenagers and a Pharmacological Discussion of Their Hallucinations
    (INFORMA HEALTHCARE, TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2011) Cruz, Silvia L.; Domínguez, Mario; CINVESTAV, Dept Farmacobiol, Mexico City 14330, DF, Mexico; slcruz@cinvestav.mx
    This work describes the solvent-induced hallucinatory experiences of 10 male and seven female teenagers in Mexico City from 1998 to 2000. The youth were recruited from public schools through a combined snowball and convenience sampling procedure. Inclusion criteria were: 13--18 years of age, school attendance, living with family, and weekly toluene-based solvent misuse. Interested students were interviewed and transcripts were analyzed. Hallucinations and illusions were common, including changes in color perception, visual, somatic, auditory, and tactile hallucinations. Some users described their hallucinatory experience as being able to be shared by a group and modulated by their environment. The pharmacological linkages with hallucinations are discussed. The study's limitations are noted
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    Role of nociceptin/orphanin FQ and the pseudopeptide [Phe1_(CH2NH)Gly2]-nociceptin(1–13)-NH2 and their interaction with classic opioids in the modulation of thermonociception in the land snail Helix aspersa
    (2008) Miller-Pérez, Carolina; Sánchez-Islas, Eduardo; Pellicer, Francisco; Rodríguez-Manzo, Gabriela; Cruz, Silvia L.; León-Olea, Martha; Laboratorio de Histología y Microscopía Electrónica, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría “Ramón de la Fuente Muñiz”, Calzada México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan. México D.F., C.P. 14370, México
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    Synergistic antinociceptive actions and tolerance development produced by morphine-fentanyl coadministration: correlation with _-opioid receptor internalization
    (2012) Silva-Moreno, Arturo; González-Espinosa, Claudia; León-Olea, Martha; Cruz, Silvia L.; Departamento de Farmacobiología, Cinvestav, Sede Sur. Calzada de Tenorios # 235, Col. Granjas Coapa, México DF, 14330, México.; slcruz@cinvestav.mx
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    The Latest Evidence in the Neuroscience of Solvent Misuse: An Article Written for Service Providers
    (Informa Healthcare, Telephone House, 69-77 Paul Street, London EC2A 4LQ, England, 2011) Cruz, Silvia L.; CINVESTAV, Dept Farmacobiol, Mexico City 14000, DF, Mexico; slcruz@cinvestav.mx
    This work reviews preclinical and clinical studies published during the past two decades on the cellular and behavioral effects of commonly misused solvents. In animals, acute solvent exposure produces motor impairment and antidepressant- and anxiolytic-like effects. Human intoxication from misusing solvents is similar to that of ethanol; however, hallucinations and sudden sniffing death may occur at high solvent concentrations. Among chronic misusers, there is evidence of impaired memory, increased prevalence of psychiatric disorders, and neurological damage. Solvents facilitate inhibitory neurotransmission and block excitatory mechanisms. Toluene, in particular, increases brain dopamine levels and its effects occur at concentrations that do not dissolve cell membranes; therefore, neuronal damage is not an immediate, unavoidable consequence of solvent misuse
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    Toluene impairs learning and memory, has antinociceptive effects, and modifies histone acetylation in the dentate gyrus of adolescent and adult rats
    (2012) Huerta-Rivas, Alejandra; López-Rubalcava, Carolina; Sánchez-Serrano, Sinthia L.; Valdez-Tapia, Marina; Lamas, Mónica; Cruz, Silvia L.; Departamento de Farmacobiología, Cinvestav, Sede Sur. Calzada de los Tenorios # 235, Col. Granjas Coapa, México D.F., 14330, México; slcruz@cinvestav.mx
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    Volatile Substance Misuse in Mexico: Correlates and Trends
    (INFORMA HEALTHCARE, TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2011) Villatoro, Jorge A.; Cruz, Silvia L.; Ortíz, Arturo; Medina-Mora, María Elena; Inst Nacl Psiquiatria, Dept Invest Epidemiol, Direcc Invest Epidemiol & Psicosociales, Calzada Mexico Xochimilco 101, Mexico City 14370, DF, Mexico.; slcruz@cinvestav.mx
    This paper analyzes volatile substance misuse in Mexico since the 1980s. Data were collected from national household and school surveys, epidemiological surveillance systems, and studies among special populations. Volatile substance misuse begins at 12--14 years. Prevalence is approximately 1%% in the general population, 7%% among high school students, and higher for street children. Toluene is the main solvent used, but preferences vary within population groups. Volatile substance misuse has increased among youngsters that live in families and attend school. Marijuana and volatile substances are now the drugs of choice among Mexican female high school students. The study's limitations are noted