Mostrar el registro sencillo del ítem

Speech illusions in people at clinical high risk for psychosis linked to clinical outcome

dc.creatorHird, Emely J.es_ES
dc.creatorOhmuro, Noriyukies_ES
dc.creatorAllen, Paules_ES
dc.creatorMoseley, Peteres_ES
dc.creatorKempton, Matthew J.es_ES
dc.creatorModinos, Gemmaes_ES
dc.creatorSachs, Gabrielees_ES
dc.creatorGaag, Mark van deres_ES
dc.creatorHaan, Lieuwe dees_ES
dc.creatorGadelha, Aryes_ES
dc.creatorBressan, Rodrigoes_ES
dc.creatorBarrantes-Vidal, Neuses_ES
dc.creatorRuhrmann, Stephanes_ES
dc.creatorCatalan, Anaes_ES
dc.creatorMcGuire, Philipes_ES
dc.creatorEU-GEI High Risk Study:es_ES
dc.creatorMcGuire, Philipes_ES
dc.creatorValmaggia, Lucia R.es_ES
dc.creatorKempton, Matthew J.es_ES
dc.creatorCalem, Mariaes_ES
dc.creatorTognin, Stefaniaes_ES
dc.creatorModinos, Gemmaes_ES
dc.creatorHaan, Lieuwe dees_ES
dc.creatorGaag, Mark van deres_ES
dc.creatorVelthorst, Evaes_ES
dc.creatorKraan, Tamar C.es_ES
dc.creatorDam, Daniella S. vanes_ES
dc.creatorBurger, Nadinees_ES
dc.creatorNelson, Barnabyes_ES
dc.creatorMcGorry, Patrickes_ES
dc.creatorAmminger, Günter Paules_ES
dc.creatorPantelis, Christoses_ES
dc.creatorPolitis, Athenaes_ES
dc.creatorGoodall, Joannees_ES
dc.creatorRiecher-Rössler, Anitaes_ES
dc.creatorBorgwardt, Stefanes_ES
dc.creatorRapp, Charlottees_ES
dc.creatorIttig, Sarahes_ES
dc.creatorStuderus, Eriches_ES
dc.creatorSmieskova, Renataes_ES
dc.creatorBressan, Rodrigoes_ES
dc.creatorGadelha, Aryes_ES
dc.creatorBrietzke, Elisaes_ES
dc.creatorAsevedo, Gracciellees_ES
dc.creatorAsevedo, Elsones_ES
dc.creatorZugman, Andrees_ES
dc.creatorBarrantes-Vidal, Neuses_ES
dc.creatorDomínguez-Martínez, Tecellies_ES
dc.creatorTorrecilla, Pilares_ES
dc.creatorKwapil, Thomas R.es_ES
dc.creatorMonsonet, Maneles_ES
dc.creatorHinojosa, Lídiaes_ES
dc.creatorKazes, Mathildees_ES
dc.creatorDaban, Clairees_ES
dc.creatorBourgin, Juliees_ES
dc.creatorGay, Olivieres_ES
dc.creatorMam-Lam-Fook, Céliaes_ES
dc.creatorKrebs, Marie-Odilees_ES
dc.creatorNordholm, Dortees_ES
dc.creatorRanders, Lassees_ES
dc.creatorKrakauer, Kristinees_ES
dc.creatorGlenthøj, Louisees_ES
dc.creatorGlenthøj, Birtees_ES
dc.creatorNordentoft, Meretees_ES
dc.creatorRuhrmann, Stephanes_ES
dc.creatorGebhard, Dominikaes_ES
dc.creatorArnhold, Juliaes_ES
dc.creatorKlosterkötter, Joachimes_ES
dc.creatorSachs, Gabrielees_ES
dc.creatorLasser, Irises_ES
dc.creatorWinklbaur, Bernadettees_ES
dc.creatorDelespaul, Philipe A.es_ES
dc.creatorRutten, Bart P.es_ES
dc.creatorOsl, Jim vanes_ES
dc.date2023
dc.date.accessioned2025-03-18T18:03:00Z
dc.date.available2025-03-18T18:03:00Z
dc.date.issued2023
dc.identifierJC17DIEP23es_ES
dc.identifier.issn0586-7614
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/8251
dc.identifier.urihttps://doi.org/10.1093/schbul/sbac163
dc.descriptionBackground and hypothesis: Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech (termed speech illusions [SIs]) in noise in CHR participants and examined whether this was associated with adverse clinical outcomes. Study design: At baseline, 344 CHR participants and 67 healthy controls were presented with a computerized white noise task and asked whether they heard speech, and whether speech was neutral, affective, or whether they were uncertain about its valence. After 2 years, we assessed whether participants transitioned to psychosis, or remitted from the CHR state, and their functioning. Study results: CHR participants had a lower sensitivity to the task. Logistic regression revealed that a bias towards hearing targets in stimuli was associated with remission status (OR = 0.21, P = 042). Conversely, hearing SIs with uncertain valence at baseline was associated with reduced likelihood of remission (OR = 7.72. P = .007). When we assessed only participants who did not take antipsychotic medication at baseline, the association between hearing SIs with uncertain valence at baseline and remission likelihood remained (OR = 7.61, P = .043) and this variable was additionally associated with a greater likelihood of transition to psychosis (OR = 5.34, P = .029). Conclusions: In CHR individuals, a tendency to hear speech in noise, and uncertainty about the affective valence of this speech, is associated with adverse outcomes. This task could be used in a battery of cognitive markers to stratify CHR participants according to subsequent outcomes.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherOxford University Presses_ES
dc.relation49(2):339-349
dc.rightsAcceso Cerradoes_ES
dc.titleSpeech illusions in people at clinical high risk for psychosis linked to clinical outcomees_ES
dc.typeArtículoes_ES
dc.contributor.affiliationDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
dc.contributor.emailemily.hird@kcl.ac.uk
dc.relation.jnabreviadoSCHIZOPHR BULL
dc.relation.journalSchizophrenia Bulletin
dc.identifier.placeEstados Unidos
dc.date.published2023
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1745-1701
dc.identifier.doi10.1093/schbul/sbac163
dc.subject.kwSignal-detection
dc.subject.kwWhite noise task
dc.subject.kwUncertainty
dc.subject.kwRemission
dc.subject.kwTransition


Ficheros en el ítem

FicherosTamañoFormatoVer

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem