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The effect of stressful life events on the risk for psychosis: differences between Mexican at clinical and familial high risk

dc.creatorNieto, Lourdeses_ES
dc.creatorDomínguez-Martínez, Tecellies_ES
dc.creatorNavarrete, Lauraes_ES
dc.creatorRosel-Vales, Mauricioes_ES
dc.creatorSaracco-Álvarez, Ricardoes_ES
dc.creatorCelada-Borja, Césares_ES
dc.creatorRascón-Gasca, Maria Luisaes_ES
dc.creatorMoncayo Samperio, Luis Gerardoes_ES
dc.date2023
dc.date.accessioned2025-02-25T18:08:06Z
dc.date.available2025-02-25T18:08:06Z
dc.date.issued2023
dc.identifierJC11DIEP23es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/8228
dc.identifier.urihttps://doi.org/10.3389/fpsyt.2023.1254993
dc.descriptionBackground: Stressful life events (SLEs) in the development of early psychosis have been little studied in low-income countries. This study examines differences in the prevalence of SLEs in Mexican at clinical high risk (CHR) and those with familial high risk for psychosis who do not meet CHR criteria (non-CHR FHR). We also analyze the association between SLEs and CHR. Methods: Participants included 43 persons with CHR and 35 with non-CHR FHR. CHR criteria were assessed with the Comprehensive Assessment of At-Risk Mental State. SLEs were assessed using the Questionnaire of Stressful Life Events. Results: Participants with CHR reported more SLEs associated with negative academic experiences than those in the non-CHR FHR group. Bullying (OR = 7.77, 95% CI [1.81, 33.32]) and low educational level (OR = 21.25, 95% CI [5.19, 46.90]) were the strongest predictors of CHR, while starting to live with a partner (OR = 0.26, 95% CI [0.10, 0.84]) was associated with a lower risk of CHR. Conclusion: Negative school experiences increase the risk of psychosis, particularly bullying, suggesting that schools may be ideal settings for implementing individual preventive strategies to reduce risk factors and increase protective factors to improve the prognosis of those at risk of developing psychosis. In Latin America, there are multiple barriers to early intervention in psychosis. It is thus crucial to identify risk and protective factors at the onset and in the course of psychosis in order to design effective preventive interventions.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherFrontiers Research Foundationes_ES
dc.relation14:1254993
dc.rightsAcceso Cerradoes_ES
dc.titleThe effect of stressful life events on the risk for psychosis: differences between Mexican at clinical and familial high riskes_ES
dc.typeArtículoes_ES
dc.contributor.affiliationCentro de Investigación en Salud Mental Global, Dirección de Investigaciones Epidemiológicas y Psicosociales, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz-UNAM, Mexico City, Mexico
dc.contributor.emailnietoglourdes@gmail.com (Lourdes Nieto)
dc.relation.jnabreviadoFRONT PSYCHIATRY
dc.relation.journalFrontiers in Psychiatry
dc.identifier.placeSuiza
dc.identifier.placeSuiza
dc.date.published2023
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1664-0640
dc.identifier.doi10.3389/fpsyt.2023.1254993
dc.subject.kwStressful life events
dc.subject.kwClinical high risk
dc.subject.kwFamilial high risk
dc.subject.kwPsychosis
dc.subject.kwBullyings
dc.subject.kwDeveloping countrie


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