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dc.creatorValencia, Marceloes_ES
dc.creatorMedina, Rafaeles_ES
dc.creatorCalixto, Eduardoes_ES
dc.creatorRodríguez, Noemíes_ES
dc.date2022
dc.date.accessioned2024-11-11T17:22:38Z
dc.date.available2024-11-11T17:22:38Z
dc.date.issued2022
dc.identifierJC54DIEP22es_ES
dc.identifier.issn1176-6328
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/8102
dc.identifier.urihttps://doi.org/10.2147/NDT.S370449
dc.descriptionThe human brain is the most cognitively capable of mammalian brains, endowed as it is with an overdeveloped cerebral cortex that, in parallel, renders it vulnerable to mental disorders. Schizophrenia is the expression of the dysregulation of the neuronal activity of cortical and subcortical regions due to modifications in the levels of the various neurotransmitters, especially of dopamine, with a reciprocal, intimate relationship among genes with environmental and psychosocial factors. If the dopaminergic system increases the function prefrontal cortex will be reduced: this is the main reason of social, occupational and familiar disruption. The present article describes the function of the brain in schizophrenia and its relation with anatomical, physiological, and genetic changes, in addition to identifying, psychosocial and family factors that can be determinant in the functionality of the patient. A review of national and international bibliography was conducted bearing in mind the following variables: functioning at the cerebral level; psychosocial functioning, familial functioning, disability, and functionality in persons with schizophrenia. Due to the variety of the issues included in this review, it can be concluded that schizophrenia is the product of a complex array of symptoms, deficits and disabilities. It was identified that there is a reciprocal confluence of diverse genetic, psychosocial, familial, environmental, educative, and social factors which affect the functionality of persons with this disorder. The latter makes it necessary to study the patient taking into consideration all of these components in an integral manner.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherDove Medical Presses_ES
dc.relation18:2069-2082
dc.rightsAcceso Cerradoes_ES
dc.titleCerebral, psychosocial, family functioning and disability of persons with schizophreniaes_ES
dc.typeArtículoes_ES
dc.contributor.affiliationDepartment of Innovation and Global Health, Epidemiologic and Psychosocial Research Direction; National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico
dc.contributor.emailvalenc@imp.edu.mx (Marcelo Valencia)
dc.relation.jnabreviadoNEUROPSYCHIATR DIS TREAT
dc.relation.journalNeuropsychiatric Disease and Treatment
dc.identifier.placeNueva Zelanda
dc.date.published2022
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1178-2021
dc.identifier.doi10.2147/NDT.S370449
dc.subject.kwCerebral functioning
dc.subject.kwPsychosocial and family functioning
dc.subject.kwDisability and functionality
dc.subject.kwSchizophrenia


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