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Neuropsychological validation of a brief quiz to examine comprehension of consent information in observational studies of substance users

dc.creatorToledo-Fernández, Aldebaránes_ES
dc.creatorSánchez-Domínguez, Ricardoes_ES
dc.creatorVillalobos-Gallegos, Luises_ES
dc.creatorPérez-López, Alejandroes_ES
dc.creatorMacías-Flores, Alanes_ES
dc.creatorMarín-Navarrete, Rodrigoes_ES
dc.date2020
dc.date.accessioned2023-11-30T17:18:43Z
dc.date.available2023-11-30T17:18:43Z
dc.date.issued2020
dc.identifierJC18SIC20es_ES
dc.identifier.issn1050-8422
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/7846
dc.identifier.urihttps://doi.org/10.1080/10508422.2020.1822175
dc.descriptionThe objective of this study was to determine the accuracy of a brief informed consent quiz (ICQ) to detect consent comprehension in individuals with cognitive impairment (as a proxy of incomprehension) and to explore the degree to which cognitive domains and recent substance use, independently, predict comprehension. We performed a secondary analysis of two cross-sectional studies in individuals with substance use disorders. The ICQ total score was used as the index test and the Montreal Cognitive Assessment (MoCA) as reference standard in receiver operating characteristic curves. Two independent multiple binary logistic regression models were performed using cognitive domains and days of recent substance use as predictors of ICQ outcome. We analyzed data from 215 and 251 participants, respectively. The ICQ showed moderate accuracy for major cognitive impairment (MoCA ≤ 21) (area under the curve ~ 77) and lower accuracy for mild impairment (MoCA ≤ 24) (area under the curve ~ 65). Optimal cutoff score was set at 10 points or less for detecting comprehension difficulty. Lower scores in Short-Term Memory, Attention, Language, and Orientation increased the probability of failing the ICQ. A procedure including both the ICQ and cognitive screening measure could improve the accuracy of consent comprehension assessments.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherLawrence Erlbaum Associateses_ES
dc.relation31:8, 545-556
dc.rightsAcceso Cerradoes_ES
dc.titleNeuropsychological validation of a brief quiz to examine comprehension of consent information in observational studies of substance userses_ES
dc.typeArtículoes_ES
dc.contributor.affiliationFacultad de Psicología, Universidad Anáhuac México
dc.contributor.emailaldebaran.toledofe@anahuac.mx (Aldebarán Toledo-Fernández)
dc.relation.jnabreviadoETHICS BEHAV
dc.relation.journalEthics & Behavior
dc.identifier.placeEstados Unidos
dc.date.published2020
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1532-7019
dc.identifier.doi10.1080/10508422.2020.1822175
dc.subject.kwInformed consent
dc.subject.kwComprehension
dc.subject.kwNeurocognitive disorder
dc.subject.kwCognitive impairment
dc.subject.kwSubstance use


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