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IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients
| dc.creator | Mendieta, Daniela | es_ES |
| dc.creator | de la Cruz-Aguilera, Dora Luz | es_ES |
| dc.creator | Barrerra-Villalpando, Maria Isabel | es_ES |
| dc.creator | Becerril-Villanueva, Enrique | es_ES |
| dc.creator | Arreola, Rodrigo | es_ES |
| dc.creator | Hernández-Ferreira, Erick | es_ES |
| dc.creator | Pérez-Tapia, Sonia Mayra | es_ES |
| dc.creator | Pérez-Sánchez, Gilberto | es_ES |
| dc.creator | Garcés-Álvarez, María Eugenia | es_ES |
| dc.creator | Aguirre-Cruz, Lucinda | |
| dc.creator | Velasco-Velázquez, Marco Antonio | |
| dc.creator | Pavón, Lenin | |
| dc.date | 2016 | |
| dc.date.accessioned | 2023-10-23T19:19:23Z | |
| dc.date.available | 2023-10-23T19:19:23Z | |
| dc.date.issued | 2016 | |
| dc.identifier.issn | 0165-5728 | |
| dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/7793 | |
| dc.identifier.uri | http://dx.doi.org/10.1016/j.jneuroim.2015.11.011 | |
| dc.description | Fibromyalgia (FM) is a chronic disease that has been linked to inflammatory reactions and changes in the system ic levels of proinflammatory cytokines that modulate responses in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. We found that concentrations of IL-6 and IL-8 were elevated in FM patients. Both cytokines correlated with clinical scores, suggesting that IL-6 and IL-8 have additive or synergistic effects in perpetuating the chronic pain in FM patients. These findings indicate that IL-6 and IL-8 are two of the most con stant inflammatory mediators in FM and that their levels correlate significantly with the severity of symptoms. | |
| dc.format | ||
| dc.language.iso | eng | |
| dc.publisher | Elsevier | |
| dc.relation | 15(290)22-25 | |
| dc.rights | Acceso Cerrado | |
| dc.title | IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients | es_ES |
| dc.type | Artículo | |
| dc.contributor.affiliation | Clinical Service, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexico | |
| dc.contributor.email | danemend@hotmail.com (D. Mendieta) | |
| dc.contributor.email | cruza_dl@hotmail.com (D.L.D. la Cruz-Aguilera) | |
| dc.contributor.email | maribel_barrerav@yahoo.com.mx (M.I. Barrera-Villalpando) | |
| dc.contributor.email | lusenbeve@yahoo.com (E. Becerril-Villanueva) | |
| dc.contributor.email | lahunsotz@yahoo.com.mx (R. Arreola) | |
| dc.contributor.email | erick.hdz.ferreira@gmail.com (E. Hernández-Ferreira) | |
| dc.contributor.email | smpt.2011@hotmail.com (S.M. Pérez-Tapia) | |
| dc.contributor.email | gipersanchez@hotmail.com (G. Pérez-Sánchez) | |
| dc.contributor.email | me.garces.alvarez@live.com.mx (M.E. Garcés-Alvarez) | |
| dc.contributor.email | mariluci_aguirre@hotmail.com (L. Aguirre-Cruz) | |
| dc.contributor.email | marcovelasco@unam.mx (M.A. Velasco-Velázquez) | |
| dc.contributor.email | lkuriaki@imp.edu.mx (L. Pavón) | |
| dc.relation.jnabreviado | J NEUROIMMUNOL | |
| dc.relation.journal | Journal of Neuroimmunology | |
| dc.identifier.place | Países Bajos | |
| dc.date.published | 2016 | |
| dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | |
| dc.identifier.eissn | 1872-8421 | |
| dc.identifier.doi | 10.1016/j.jneuroim.2015.11.011 | |
| dc.subject.kw | Fibromyalgia | |
| dc.subject.kw | IL-6 | |
| dc.subject.kw | IL-8 | |
| dc.subject.kw | FIQ | |
| dc.subject.kw | Inflammation |
