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Sex differences in cognitive functioning of patients at-risk for psychosis and healthy controls: results from the European Gene-Environment Interactions study

dc.creatorMenghini-Müller, Stephaniees_ES
dc.creatorStuderus, Eriches_ES
dc.creatorIttig, Sarahes_ES
dc.creatorValmaggia, Lucia R.es_ES
dc.creatorKempton, Matthew J.es_ES
dc.creatorGaag, Mark van deres_ES
dc.creatorHaan, Lieuwe dees_ES
dc.creatorNelson, Barnabyes_ES
dc.creatorBressan, Rodrigo A.es_ES
dc.creatorBarrantes-Vidal, Neuses_ES
dc.creatorJantac, Céliaes_ES
dc.creatorNordentoft, Meretees_ES
dc.creatorRuhrmann, Stephanes_ES
dc.creatorSachs, Garbielees_ES
dc.creatorRutten, Bart P.es_ES
dc.creatorOs, Jim vanes_ES
dc.creatorRiecher-Rössler, Anitaes_ES
dc.creatorEU GEI High Risk Study Group:es_ES
dc.creatorMcGuire, Philipes_ES
dc.creatorValmaggia, Lucia R.es_ES
dc.creatorKempton, Matthew J.es_ES
dc.creatorCalem, Mariaes_ES
dc.creatorTognin, Stefaniaes_ES
dc.creatorModinos, Gemmaes_ES
dc.creatorHaan, Lieuwe dees_ES
dc.creatorGaag, Mark van deres_ES
dc.creatorVelthorst, Evaes_ES
dc.creatorKraan, Tamar C.es_ES
dc.creatorDam, Daniella S. vanes_ES
dc.creatorBurger, Nadinees_ES
dc.creatorNelson, Barnabyes_ES
dc.creatorMcGorry, Patrickes_ES
dc.creatorAmminger, G. Paules_ES
dc.creatorPantelis, Christoses_ES
dc.creatorPolitis, Athenaes_ES
dc.creatorGoodall, Joannees_ES
dc.creatorRiecher-Rössler, Anitaes_ES
dc.creatorBorgwardt, Stefanes_ES
dc.creatorRapp, Charlottees_ES
dc.creatorIttig, Sarahes_ES
dc.creatorStuderus, Eriches_ES
dc.creatorSmieskova, Renataes_ES
dc.creatorBressan, Rodrigoes_ES
dc.creatorGadelha, Aryes_ES
dc.creatorBrietzke, Elisaes_ES
dc.creatorAsevedo, Gracciellees_ES
dc.creatorAsevedo, Elsones_ES
dc.creatorZugman, Andrees_ES
dc.creatorBarrantes-Vidal, Neuses_ES
dc.creatorDomínguez-Martínez, Tecellies_ES
dc.creatorRacioppi, Annaes_ES
dc.creatorHinojosa-Marqués, Lídiaes_ES
dc.creatorKwapil, Thomas R.es_ES
dc.creatorMonsonet, Maneles_ES
dc.creatorKazes, Mathildees_ES
dc.creatorDaban, Clairees_ES
dc.creatorBourgin, Juliees_ES
dc.creatorGay, Olivieres_ES
dc.creatorMam-Lam-Fook, Céliaes_ES
dc.creatorKrebs, Marie-Odilees_ES
dc.creatorNordholm, Dortees_ES
dc.creatorRanders, Lassees_ES
dc.creatorKrakauer, Kristinees_ES
dc.creatorGlenthøj, Louisees_ES
dc.creatorGlenthøj, Birtees_ES
dc.creatorNordentoft, Meretees_ES
dc.creatorRuhrmann, Stephanes_ES
dc.creatorGebhard, Dominikaes_ES
dc.creatorArnhold, Juliaes_ES
dc.creatorKlosterkötter, Joachimes_ES
dc.creatorSachs, Gabrielees_ES
dc.creatorLasser, Irises_ES
dc.creatorWinklbaur, Bernadettees_ES
dc.creatorDelespaul, Philippe A.es_ES
dc.creatorRutten, Bart P.es_ES
dc.creatorOs, Jim vanes_ES
dc.date2020
dc.date.accessioned2023-09-05T16:33:15Z
dc.date.available2023-09-05T16:33:15Z
dc.date.issued2020
dc.identifierJC27DIEP20es_ES
dc.identifier.issn0924-9338
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/7752
dc.identifier.urihttps://doi.org/10.1192/j.eurpsy.2019.10
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315874/
dc.descriptionBackground: Sex differences in cognitive functioning have long been recognized in schizophrenia patients and healthy controls (HC). However, few studies have focused on patients with an at-risk mental state (ARMS) for psychosis. Thus, the aim of the present study was to investigate sex differences in neurocognitive performance in ARMS patients compared with HC. Methods: The data analyzed in this study were collected within the multicenter European Gene-Environment Interactions study (11 centers). A total of 343 ARMS patients (158 women) and 67 HC subjects (33 women) were included. All participants completed a comprehensive neurocognitive battery. Linear mixed effects models were used to explore whether sex differences in cognitive functioning were present in the total group (main effect of sex) and whether sex differences were different for HC and ARMS (interaction between sex and group). Results: Women performed better in social cognition, speed of processing, and verbal learning than men regardless of whether they were ARMS or HC. However, only differences in speed of processing and verbal learning remained significant after correction for multiple testing. Additionally, ARMS patients displayed alterations in attention, current IQ, speed of processing, verbal learning, and working memory compared with HC. Conclusions: Findings indicate that sex differences in cognitive functioning in ARMS are similar to those seen between healthy men and women. Thus, it appears that sex differences in cognitive performance may not be specific for ARMS, a finding resembling that in patients with schizophrenic psychoses.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherCambridge University Presses_ES
dc.relation63(1):e25
dc.rightsAcceso Cerradoes_ES
dc.titleSex differences in cognitive functioning of patients at-risk for psychosis and healthy controls: results from the European Gene-Environment Interactions studyes_ES
dc.typeArtículoes_ES
dc.contributor.affiliationUniversity of Basel, Department of Psychiatry, Basel, Switzerland.
dc.contributor.emailanita.riecher@unibas.ch (Anita Riecher-Rössler)
dc.relation.jnabreviadoEUR PSYCHIATRY
dc.relation.journalEuropean Psychiatry
dc.identifier.placeInglaterra
dc.date.published2020
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1778-3585
dc.identifier.doi10.1192/j.eurpsy.2019.10
dc.subject.kwClinical high-risk
dc.subject.kwCognition
dc.subject.kwGender differences
dc.subject.kwRisk for psychosis


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