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Relationship between jumping to conclusions and clinical outcomes in people at clinical high-risk for psychosis

dc.creatorCatalan, Anaes_ES
dc.creatorTognin, Stefaniaes_ES
dc.creatorKempton, Matthew J.es_ES
dc.creatorStahl, Danieles_ES
dc.creatorSalazar de Pablo, Gonzaloes_ES
dc.creatorNelson, Barnabyes_ES
dc.creatorPantelis, Christoses_ES
dc.creatorRiecher-Rössler, Anitaes_ES
dc.creatorBressan, Rodrigoes_ES
dc.creatorBarrantes-Vidal, Neuses_ES
dc.creatorKrebs, Marie-Odilees_ES
dc.creatorNordentoft, Meretees_ES
dc.creatorRuhrmann, Stephanes_ES
dc.creatorSachs, Gabrielees_ES
dc.creatorRutten, Bart P. F.es_ES
dc.creatorOs, Jim vanes_ES
dc.creatorHaan, Lieuwe dees_ES
dc.creatorGaag, Mark van deres_ES
dc.creatorEU-GEI High Risk Studyes_ES
dc.creatorValmaggia, Lucia R.es_ES
dc.creatorMcGuire, Philipes_ES
dc.creatorDomínguez-Martínez, Tecellies_ES
dc.date2022
dc.date.accessioned2023-08-23T17:30:39Z
dc.date.available2023-08-23T17:30:39Z
dc.date.issued2022
dc.identifierJC09DIEP20es_ES
dc.identifier.issn0033-2917
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/7734
dc.identifier.urihttps://doi.org/10.1017/S0033291720003396
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226382/
dc.descriptionBackground: Psychosis is associated with a reasoning bias, which manifests as a tendency to 'jump to conclusions'. We examined this bias in people at clinical high-risk for psychosis (CHR) and investigated its relationship with their clinical outcomes. Methods: In total, 303 CHR subjects and 57 healthy controls (HC) were included. Both groups were assessed at baseline, and after 1 and 2 years. A 'beads' task was used to assess reasoning bias. Symptoms and level of functioning were assessed using the Comprehensive Assessment of At-Risk Mental States scale (CAARMS) and the Global Assessment of Functioning (GAF), respectively. During follow up, 58 (16.1%) of the CHR group developed psychosis (CHR-T), and 245 did not (CHR-NT). Logistic regressions, multilevel mixed models, and Cox regression were used to analyse the relationship between reasoning bias and transition to psychosis and level of functioning, at each time point. Results: There was no association between reasoning bias at baseline and the subsequent onset of psychosis. However, when assessed after the transition to psychosis, CHR-T participants showed a greater tendency to jump to conclusions than CHR-NT and HC participants (55, 17, 17%; χ2 = 8.13, p = 0.012). There was a significant association between jumping to conclusions (JTC) at baseline and a reduced level of functioning at 2-year follow-up in the CHR group after adjusting for transition, gender, ethnicity, age, and IQ. Conclusions: In CHR participants, JTC at baseline was associated with adverse functioning at the follow-up. Interventions designed to improve JTC could be beneficial in the CHR population.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherCambridge University Presses_ES
dc.relation52(8):1569-1577
dc.rightsAcceso Cerradoes_ES
dc.titleRelationship between jumping to conclusions and clinical outcomes in people at clinical high-risk for psychosises_ES
dc.typeArtículoes_ES
dc.contributor.affiliationDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
dc.contributor.emailana.catalan@kcl.ac.uk (Ana Catalan)
dc.relation.jnabreviadoPSYCHOL MED
dc.relation.journalPsychological Medicine
dc.identifier.placeInglaterra
dc.date.published2022
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1469-8978
dc.identifier.eissn1469-8978
dc.identifier.doi10.1017/S0033291720003396
dc.subject.kwFunctioning
dc.subject.kwPsychosis
dc.subject.kwTransition to psychosis
dc.subject.kwUltra high-risk


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