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The bidirectional associations between psychotic experiences and DSM-IV Mental Disorders

dc.creatorMcGrath, John J.es_ES
dc.creatorSaha, Sukantaes_ES
dc.creatorAl-Hamzawi, Alies_ES
dc.creatorAndrade, Lauraes_ES
dc.creatorBenjet, Corinaes_ES
dc.creatorBromet, Evelyn J.es_ES
dc.creatorBrowne, Mark Oakleyes_ES
dc.creatorCaldas de Almeida, Jose M.es_ES
dc.creatorChiu, Wai Tates_ES
dc.creatorDemyttenaere, Koenes_ES
dc.creatorFayyad, Johnes_ES
dc.creatorFlorescu, Silviaes_ES
dc.creatorGirolamo, Giovanni dees_ES
dc.creatorGureje, Oyees_ES
dc.creatorHaro, Josep Mariaes_ES
dc.creatorHave, Margreet tenes_ES
dc.creatorHu, Chiyies_ES
dc.creatorKovess-Masfety, Vivianees_ES
dc.creatorLim, Carmen C.W.es_ES
dc.creatorNavarro-Mateu, Fernandoes_ES
dc.creatorSampson, Nancyes_ES
dc.creatorPosada-Villa, Josées_ES
dc.creatorKendler, Kenneth S.es_ES
dc.creatorKessler, Ronald C.es_ES
dc.date2016
dc.date.accessioned2023-02-03T16:53:02Z
dc.date.available2023-02-03T16:53:02Z
dc.date.issued2016
dc.identifierJC01EP16es_ES
dc.identifier.issn0002-953X
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/7675
dc.identifier.urihttps://doi.org/10.1176/appi.ajp.2016.15101293
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175400/
dc.descriptionObjective: While it is now recognized that psychotic experiences are associated with an increased risk of later mental disorders, we lack a detailed understanding of the reciprocal time-lagged relationships between first onsets of psychotic experiences and mental disorders. Using data from World Health Organization World Mental Health (WMH) Surveys, the authors assessed the bidirectional temporal associations between psychotic experiences and mental disorders. Method: The WMH Surveys assessed lifetime prevalence and age at onset of psychotic experiences and 21 common DSM-IV mental disorders among 31,261 adult respondents from 18 countries. Discrete-time survival models were used to examine bivariate and multivariate associations between psychotic experiences and mental disorders. Results: Temporally primary psychotic experiences were significantly associated with subsequent first onset of eight of the 21 mental disorders (major depressive disorder, bipolar disorder, generalized anxiety disorder, social phobia, posttraumatic stress disorder, adult separation anxiety disorder, bulimia nervosa, and alcohol abuse), with odds ratios ranging from 1.3 (95% CI=1.2-1.5) for major depressive disorder to 2.0 (95% CI=1.5-2.6) for bipolar disorder. In contrast, 18 of 21 primary mental disorders were significantly associated with subsequent first onset of psychotic experiences, with odds ratios ranging from 1.5 (95% CI=1.0-2.1) for childhood separation anxiety disorder to 2.8 (95% CI=1.0-7.8) for anorexia nervosa. Conclusions: While temporally primary psychotic experiences are associated with an elevated risk of several subsequent mental disorders, these data show that most mental disorders are associated with an elevated risk of subsequent psychotic experiences. Further investigation of the underlying factors accounting for these time-order relationships may shed light on the etiology of psychotic experiences.es_ES
dc.formatPDFes_ES
dc.language.isoenges_ES
dc.publisherAmerican Psychiatric Associationes_ES
dc.relation173(10):997-1006
dc.rightsAcceso Cerrado
dc.titleThe bidirectional associations between psychotic experiences and DSM-IV Mental Disorderses_ES
dc.typeArtículoes_ES
dc.contributor.affiliationFrom the Queensland Centre for Mental Health Research, Park Centre for Mental Health, Wacol, Australia
dc.contributor.emailj.mcgrath@uq.edu.au
dc.relation.jnabreviadoAM J PSYCHIATRY
dc.relation.journalAmerican Journal of Psychiatry
dc.identifier.placeEstados Unidos
dc.date.published2016
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
dc.identifier.eissn1535-7228
dc.identifier.doi10.1176/appi.ajp.2016.15101293


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