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dc.creatorLevy, Alejandro V.
dc.creatorGomez-Mont, Franciscoes_ES
dc.creatorVolkow, Nora D.es_ES
dc.creatorCorona, Juan F.es_ES
dc.creatorBrodie, Jonathan D.es_ES
dc.creatorCancro, Robertes_ES
dc.date.accessioned2017-06-30T04:03:36Z
dc.date.available2017-06-30T04:03:36Z
dc.date.issued1992es_ES
dc.identifier2479es_ES
dc.identifier.issn0161-5505es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/7120
dc.identifier.urihttps://jnm.snmjournals.org/content/33/2/287es_ES
dc.language.isoenges_ES
dc.publisherSociety of Nuclear Medicine Country of Publication: UNITED STATES NLM ID: 0217410es_ES
dc.relation33 (2) 287-295 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleSpatial low frequency pattern analysis in positron emission tomography: a study between normals and schizophrenics.es_ES
dc.typearticlees_ES
dc.contributor.affiliationNathan S. Kline Institute for Psychiatric Research, Orangeburg, New Yorkes_ES
dc.relation.jnabreviadoJ NUCL MEDes_ES
dc.relation.journalJournal of nuclear medicinees_ES
dc.identifier.placeChicagoes_ES
dc.date.published1992es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México.es_ES
dc.identifier.eissn1535-5667es_ES
dc.description.monthFebes_ES
dc.description.abstractotrodiomaUsing the two-dimensional Fourier transform and the brain's centroidal principal axis, a method is developed for the analysis of PET metabolic brain images without the use of predefined anatomic regions of interest. We applied the method to images from a group of 11 normal and 12 medicated schizophrenics tested under resting conditions and under a visual task. A cortical/subcortical spatial pattern was found to be significant in two directions| anterior/posterior and chiasmatic (left-anterior/right-posterior). The best individual clinical classification (Jackknife classification) occurred under visual task at two axial brain levels: at the basal ganglia with correct classification rates of 91% and 84%, while the cerebellum had rates of 82% and 92%. These high classification rates were obtained using only the four coefficients of the lowest spatial frequency. These results point to the generalized brain dysfunction of regional glucose metabolism in chronic medicated schizophrenics both at rest and at a visual image-tracking taskes_ES


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