Mostrar el registro sencillo del ítem

Preemptive effect of nucleus of the solitary tract stimulation on amygdaloid kindling in freely moving cats

dc.creatorMagdaleno-Madrigal, Víctor M.
dc.creatorMartínez-Vargas, David
dc.creatorValdés-Cruz, Alejandro
dc.creatorAlmazán-Alvarado, Salvador
dc.creatorFernández-Mas, Rodrigo
dc.date.accessioned2017-06-30T03:43:21Z
dc.date.available2017-06-30T03:43:21Z
dc.date.issued2010es_ES
dc.identifier2174es_ES
dc.identifier.issn0013-9580es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/6823
dc.identifier.urihttps://doi.org/10.1111/j.1528-1167.2009.02337.xes_ES
dc.language.isoenges_ES
dc.publisherWiley-Blackwell, Commerce Place, 350 Main ST, Malden 02148, MA USAes_ES
dc.relation51 (3) 438-444 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshVagus nerve-Stimulationes_ES
dc.subject.meshDaily electrical-Stimulationes_ES
dc.subject.meshLimbic motor seizureses_ES
dc.subject.meshPartial epilepsyes_ES
dc.subject.meshBrain-stemes_ES
dc.subject.meshRatses_ES
dc.subject.meshSuppressiones_ES
dc.subject.meshEfficacyes_ES
dc.titlePreemptive effect of nucleus of the solitary tract stimulation on amygdaloid kindling in freely moving catses_ES
dc.typearticlees_ES
dc.contributor.affiliationInst Nacl Psiquiatria Ramon de la Fuente Muniz, Lab Neurofisiol Control & Regulac, Direcc Invest Neurociencias, Calz Mexico Xochimilco 101, Mexico City 14370, DF, Mexico.es_ES
dc.contributor.emailmaleno@imp.edu.mxes_ES
dc.relation.jnabreviadoEPILEPSIAes_ES
dc.relation.journalEpilepsiaes_ES
dc.identifier.placeMaldenes_ES
dc.date.published2010es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México.es_ES
dc.identifier.eissn1528-1167es_ES
dc.identifier.doi10.1111/j.1528-1167.2009.02337.x   es_ES
dc.description.monthMares_ES
dc.description.abstractotrodiomaPurpose: The nucleus of the solitary tract (NTS) is a primary site where vagal afferents terminate. The aim of this study was to analyze the preemptive effect of NTS electrical stimulation on daily amygdaloid kindling (AK) in freely moving cats. Methods: Seven adult male cats were used. Bipolar electrodes were stereotaxically implanted into both amygdalae, lateral geniculate bodies, hippocampi, and prefrontal cortices. In addition, a bipolar stainless steel electrode was implanted in the left NTS. Cats were recorded under the following experimental conditions: The NTS was stimulated for 6 days before the initiation of AK (1 min on/5 min off, 1 h total). AK was performed by stimulating the amygdala every 24 h (1 s, 60 Hz, 1 ms) until behavioral stage VI was reached. Results: The number of stimulations to reach stage VI in control animals was 23.4 +/- 3.7, in lateral tegmental field (LTF) animals was 17.0 +/- 2.1 days. Animals subjected to preemptive NTS stimulation showed a significant increase (53.8 +/- 5.9). In addition, behavioral development was retarded, with an increase in the number of stimulations required to reach stage III. In this group, overall kindling development was delayed, and amygdaloid afterdischarge duration did not show a progressive increase as was observed in the control group. Discussion: Our results indicate that preemptive NTS electrical stimulation interferes with epileptogenesis. This anticonvulsive effect could be related to the activation of certain structures that inhibit seizure development. Therefore, results suggest that NTS mediates the anticonvulsive effect of vagus nerve stimulation.es_ES
dc.subject.kwLeña amigdalinoes_ES
dc.subject.kwEstimulación del nervio vagoes_ES
dc.subject.kwNúcleo del tracto solitarioes_ES
dc.subject.kwOnda polipuntaes_ES
dc.subject.kwGatoses_ES
dc.subject.koAmygdaloid kindlinges_ES
dc.subject.koVagus nerve stimulationes_ES
dc.subject.koNucleus of the solitary tractes_ES
dc.subject.koPolyspike-wavees_ES
dc.subject.koCates_ES


Ficheros en el ítem

FicherosTamañoFormatoVer

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem