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Is there an association between fibromyalgia and below-normal levels of urinary cortisol?
dc.creator | Izquierdo-Álvarez, Silvia | |
dc.creator | Bocos-Terraz, Julia Pilar | |
dc.creator | Bancalero-Flores, José Luis | |
dc.creator | Pavón-Romero, Lenin | |
dc.creator | Serrano-Ostariz, Enrique | |
dc.creator | Alegre de Miquel, Cayetano | |
dc.date.accessioned | 2017-06-30T03:43:10Z | |
dc.date.available | 2017-06-30T03:43:10Z | |
dc.date.issued | 2008 | es_ES |
dc.identifier | 2169 | es_ES |
dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/6818 | |
dc.identifier.uri | https://doi.org/10.1186/1756-0500-1-134 | es_ES |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627911/ | es_ES |
dc.description.abstract | Background: Adynamia in fibromyalgia (FM) may be an expression of a functional deficit of the hypothalamic-pituitary-adrenal axis and be associated with below-normal levels of urinary cortisol. Our aim was to demonstrate that urinary cortisol was lower in patients with FM than in healthy subjects. Findings: We measured urinary cortisol levels for a sample of 47 women aged 29 to 64 years (mean age 53 years), diagnosed with FM 2–3 years previously, and compared the results with those for a control sample of 58 healthy women of a similar age. Samples of 24-hour urine were appropriately collected and levels of urinary cortisol were measured using the fluorescence polarization immunoassay method. The mean cortisol value for the women with FM was 65.40 ± 27.10 _g/L, significantly lower than the mean cortisol level for the control group, at 90.83 ± 38.17 _g/L (p < 0.001). Conclusion: Our study confirms that women with FM have significantly lower urinary cortisol levels than healthy women. | es_ES |
dc.language.iso | eng | es_ES |
dc.relation | 134 (1) 1-4 p. | es_ES |
dc.relation | versión del editor | es_ES |
dc.rights | acceso cerrado | es_ES |
dc.title | Is there an association between fibromyalgia and below-normal levels of urinary cortisol? | es_ES |
dc.type | article | es_ES |
dc.contributor.affiliation | Department of Biochemistry (Hormonal Section), Hospital Universitario Miguel Servet, Zaragoza, Spain | es_ES |
dc.contributor.email | sizquierdo@salud.aragon.es | es_ES |
dc.relation.jnabreviado | BMC RES NOTES | es_ES |
dc.relation.journal | BMC Research Notes | es_ES |
dc.identifier.place | Londres | es_ES |
dc.date.published | 2008 | es_ES |
dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México. | es_ES |
dc.identifier.eissn | 1756-0500 | es_ES |
dc.identifier.doi | 10.1186/1756-0500-1-134 | es_ES |
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