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Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males

dc.creatorEstrada-Reyes, R.
dc.creatorOrtíz-López, P.
dc.creatorGutiérrez-Ortíz, J.
dc.creatorMartínez-Mota, L.
dc.date.accessioned2017-06-30T03:42:42Z
dc.date.available2017-06-30T03:42:42Z
dc.date.issued2009es_ES
dc.identifier2153es_ES
dc.identifier.issn0378-8741es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/6805
dc.identifier.urihttps://doi.org/10.1016/j.jep.2009.03.032es_ES
dc.language.isoenges_ES
dc.publisherELSEVIER IRELAND LTD, ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELANDes_ES
dc.relation123, 423-429 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleTurnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted maleses_ES
dc.typearticlees_ES
dc.contributor.affiliationLaboratorio de Farmacología Conductual, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco No. 101, Col. San Lorenzo Huipulco, Delegación Tlalpan, Mexico City, 14370, Mexicoes_ES
dc.contributor.emaillucia@imp.edu.mxes_ES
dc.relation.jnabreviadoJ ETHNOPHARMACOLes_ES
dc.relation.journalJournal of Ethnopharmacologyes_ES
dc.identifier.placeClare, Irelandes_ES
dc.date.published2009es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, México.es_ES
dc.identifier.eissn1872-7573es_ES
dc.identifier.doi10.1016/j.jep.2009.03.032es_ES
dc.description.monthMares_ES
dc.description.abstractotrodiomaEthnopharmacological relevance: In folk medicine, Turnera diffusa Wild (Turnera diffusa, Turneraceae) is considered as an aphrodisiac, but its ability to restore copulation in sexually inhibited subjects has not been reported. Aim of the study: To determine whether Turnera diffusa recovers sexual behavior in sexually exhausted (SExh) male rats and to identify the main components in an aqueous extract. Materials and methods: SExh males were treated with Turnera diffusa, 20–80 mg/kg, yohimbine, 2 mg/kg, or vehicle. Results: Yohimbine and Turnera diffusa (80 mg/kg) significantly increased the percentage of males achieving one ejaculatory series and resuming a second one. In addition, Turnera diffusa significantly reduced the post-ejaculatory interval. These effectswere not associated to an increase in locomotor activity or anxietylike behaviors. The HPLC–ESI-MS analysis showed the presence of caffeine, arbutine, and flavonoids as the main compounds in the active extract. Conclusion: The results support the use of Turnera diffusa as an aphrodisiac in traditional medicine and suggest possible therapeutic properties of Turnera diffusa on sexual dysfunction. The flavonoids present in active extractmay participate in its pro-sexual effect, which is analogous to those produced by yohimbine, suggesting a shared mechanism of action.es_ES
dc.subject.kwComportamiento sexual masculinoes_ES
dc.subject.kwSexual exhaustion modeles_ES
dc.subject.kwDisfunción sexuales_ES
dc.subject.kwAfrodisíacoses_ES
dc.subject.koMale sexual behaviores_ES
dc.subject.koTurnera diffusaes_ES
dc.subject.koSexual exhaustion modeles_ES
dc.subject.koSexual dysfunctiones_ES
dc.subject.koAphrodisiacses_ES


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