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dc.creatorContreras, Carlos M.
dc.creatorMolina, Miguel
dc.creatorSaavedra, Margarita
dc.creatorMartínez-Mota, Lucía
dc.date.accessioned2017-06-30T03:42:37Z
dc.date.available2017-06-30T03:42:37Z
dc.date.issued1999es_ES
dc.identifier2148es_ES
dc.identifier.issn0031-9384es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/6803
dc.identifier.urihttps://doi.org/10.1016/S0031-9384(99)00169-9es_ES
dc.language.isoenges_ES
dc.publisherELSEVIER SCIENCE INC, 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USAes_ES
dc.relation68, 279-284 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleLateral septal neuronal firing rate increases during proestrus-estrus in the rates_ES
dc.typearticlees_ES
dc.contributor.affiliationLaboratorio de Neurofarmacolog??a, Instituto de Neuroetolog??a, Universidad Veracruzana, Mexico City, Mexicoes_ES
dc.contributor.emailcmc@bugs.invest.uv.mxes_ES
dc.relation.jnabreviadoPHYSIOL BEHAVes_ES
dc.relation.journalPhysiology & behaviores_ES
dc.identifier.placeNew York, NYes_ES
dc.date.published1999es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1873-507Xes_ES
dc.description.monthAgoes_ES
dc.description.abstractotrodiomaNeuronal activity of the lateral septal nucleus (LSN) is related to motivational and hedonic behavior. Even though some changes in mood and anxiety during proestrus and pregnancy have been reported, the possible changes in the neuronal activity of the LSN through the phases of the estrous cycle are unknown. In the present study we explored the neuronal activity from the LSN using glass micropipettes (NaCl 1 M, and Evans blue 2.5%; 3–8 M?) in 30 urethane (1 g/kg) anesthetized Wistar rats. Analysis of data included a total of 88 single-unit extracellular recordings taken from the LSN during proestrus (n = 22), estrus (n = 23), diestrus (n = 22), and metestrus (n = 21). The highest values of firing rate were found in proestrus, and the lowest in metestrus, F(3, 84) = 3.78, p < 0.01. During estrous cycles, in the phase characterized by high plasma levels of estradiol and progesterone, i.e., proestrus–estrus, the neurons from the dorsal aspect of the LSN fired at significantly (p < 0.05) higher frequencies, shorter first-order intervals and a lower coefficient of variation than those in the phase characterized by lower levels of estradiol and progesterone (metestrus–diestrus). In another group of rats (n = 12), immobility in the forced-swim test was assessed. Consistently, a longer latency (p < 0.05) for the first period of immobility and a nonsignificant trend to a lowered total time in immobility were found in proestrus and estrus. It is concluded that the higher firing rate in neurons from the dorsal aspect of the LSN during proestrus–estrus, may be associated with an increased motivation to escape from a stressful situation.es_ES
dc.subject.kwAnsiedades_ES
dc.subject.kwDepresiónes_ES
dc.subject.kwEstradioles_ES
dc.subject.kwCiclo estrales_ES
dc.subject.kwPrueba de natación forzadaes_ES
dc.subject.kwNúcleo septal laterales_ES
dc.subject.kwProgesteronaes_ES
dc.subject.koAnxietyes_ES
dc.subject.koDepressiones_ES
dc.subject.koEstradioles_ES
dc.subject.koEstrous cyclees_ES
dc.subject.koForced-swim testes_ES
dc.subject.koLateral septal nucleuses_ES
dc.subject.koProgesteronees_ES


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