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Antinociceptive effect of selected Mexican traditional medicinal species

dc.creatorDeciga-Campos, Myrna
dc.creatorGonzález-Trujano, Eva
dc.creatorNavarrete, Andrés
dc.creatorMata, Rachel
dc.date.accessioned2017-06-30T01:32:51Z
dc.date.available2017-06-30T01:32:51Z
dc.date.issued2005es_ES
dc.identifier1455es_ES
dc.identifier.issn0083-8969es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/6136
dc.language.isoenges_ES
dc.relation48, 70-72 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleAntinociceptive effect of selected Mexican traditional medicinal specieses_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartamento de Farmacia, Facultad de Quimica, UNAM, Mexico, D.F.es_ES
dc.contributor.emailmyrnadeciga@hotmail.comes_ES
dc.relation.jnabreviadoPROC WEST PHARMACOL SOCes_ES
dc.relation.journalProceedings of the Western Pharmacology Societyes_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2005es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.description.abstractotrodiomaPain is considered one of the most common complaints worldwide for which patients seek treatment. Conventional analgesic agents have played an important role in modern pain therapy, but they cause several adverse effects. Therefore, the search for new and better analgesics agents continues. The present study was designed to investigate the antinociceptive potential of six Mexican medicinal herbs commonly employed for the treatment of anti-inflammatory diseases and pain. The antinociceptive effect was tested in male mice using the writhing test. In this test intraperitoneal administration of acetic acid (0.6%) provokes abdominal contractions, movements of the body as a whole (particularly of the hind paws), twisting of dorsoabdominal muscles, and reduction in motor activity. Reduction of stretching per unit of time was considered as antinociception. Methanol-chloroform extract of the plants Exostema caribaeum, Brickellia veronicaefolia, Scaphyglottis livida, Ligusticum porteri, Gnaphalium spp, and Amphipterygium adstringens were prepared by maceration. After eliminating the solvent in vacuo, the extracts were administered orally and the antinociceptive activity determined. The results indicated that the extracts of Exostema caribaeum, Gnaphalium spp, and Amphipterygium adstringens did not produce an antinociceptive effect. However, those of Brickellia veronicaefolia, Scaphyglottis livida and Ligusticum porteri produced a significant reduction in the number of stretches in the acetic acid-induced writhing testes_ES
dc.subject.koAcetic Acides_ES
dc.subject.kodiagnostic usees_ES
dc.subject.koAnalgesicses_ES
dc.subject.kopharmacologyes_ES
dc.subject.koAnimalses_ES
dc.subject.koAnti-Inflammatory Agents, Non-Steroidales_ES
dc.subject.kopharmacologyes_ES
dc.subject.koBehavior, Animales_ES
dc.subject.kodrug effectses_ES
dc.subject.koChloroformes_ES
dc.subject.koDipyronees_ES
dc.subject.kopharmacologyes_ES
dc.subject.koMalees_ES
dc.subject.koMedicine, Traditionales_ES
dc.subject.koMethanoles_ES
dc.subject.koMexicoes_ES
dc.subject.koMicees_ES
dc.subject.koMice, Inbred ICRes_ES
dc.subject.koPain Measurementes_ES
dc.subject.kodrug effectses_ES
dc.subject.koPlant Extractses_ES
dc.subject.kopharmacologyes_ES
dc.subject.koPlants, Medicinales_ES
dc.subject.koSolventses_ES
dc.subject.koAnalgesicses_ES
dc.subject.koAnti-Inflammatory Agents, Non-Steroidales_ES
dc.subject.koPlant Extractses_ES
dc.subject.koSolventses_ES
dc.subject.koAcetic Acides_ES
dc.subject.koMethanoles_ES
dc.subject.koChloroformes_ES
dc.subject.koDipyronees_ES


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