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Hemispheric asymmetries of functional connectivity and grey matter volume in the default mode network
dc.creator | Saenger, Víctor M. | |
dc.creator | Barrios, Fernando A. | |
dc.creator | Martínez-Gudiño, María L. | |
dc.creator | Alcauter, Sarael | |
dc.date.accessioned | 2017-06-29T06:10:08Z | |
dc.date.available | 2017-06-29T06:10:08Z | |
dc.date.issued | 2012 | es_ES |
dc.identifier | 715 | es_ES |
dc.identifier.issn | 0028-3932 | es_ES |
dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/5399 | |
dc.identifier.uri | https://doi.org/10.1016/j.neuropsychologia.2012.02.014 | es_ES |
dc.language.iso | eng | es_ES |
dc.relation | 50 (7) 1308-1315 p. | es_ES |
dc.relation | versión del editor | es_ES |
dc.rights | acceso cerrado | es_ES |
dc.title | Hemispheric asymmetries of functional connectivity and grey matter volume in the default mode network | es_ES |
dc.type | article | es_ES |
dc.contributor.affiliation | Universidad Nacional Autónoma de México, Facultad de Ciencias, Universidad 3000 Circuito Exterior S/N, C.P. 04510 Ciudad Universitaria, Mexico | es_ES |
dc.contributor.email | saenger@ciencias.unam.mx | es_ES |
dc.relation.jnabreviado | NEUROPSYCHOLOGIA | es_ES |
dc.relation.journal | Neuropsychologia | es_ES |
dc.identifier.place | Oxford | es_ES |
dc.date.published | 2012 | es_ES |
dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | es_ES |
dc.identifier.doi | http://dx.doi.org/10.1016/j.neuropsychologia.2012.02.014 | es_ES |
dc.description.month | Jun | es_ES |
dc.description.abstractotrodioma | Resting state networks such as the default mode network have been widely reported. Although a plethora of information on its functional relevance has been generated, little is known about lateralization or hemisphere asymmetry within the DMN. We used high-resolution resting state fMRI and T1 3D data to investigate such asymmetries in two groups of healthy subjects, one right-handed and one left-handed. Independent component analysis and the dual regression approach were carried out to identify functional asymmetries, while voxel-based morphometry was used to identify structural asymmetries in grey matter volume within the DMN. Greater leftward functional connectivity was observed in the posterior cingulate gyrus (PCG) for both groups. Leftward functional asymmetry was observed in the thalamus and rightward functional asymmetries were observed in the middle frontal and middle/superior temporal gyrus in the right-handed group. Rightward asymmetries in grey matter volume were observed in the posterior portion of the PCG for both groups. The right-handed group exhibited leftward structural asymmetries in the anterior portion of the PCG and in the middle frontal and posterior portion of the middle temporal gyrus, while rightward asymmetries were observed in the posterior portion of the PCG and anterior portions of temporal regions. These results suggest that functional connectivity and grey matter volume are not equally distributed between hemispheres within the DMN, and that functional asymmetries are not always reflected or determined by structural asymmetries. | es_ES |
dc.subject.kw | Estado de reposo fMRI | es_ES |
dc.subject.kw | Modo de red Default | es_ES |
dc.subject.kw | Conectividad funcional | es_ES |
dc.subject.kw | Volumen de materia gris | es_ES |
dc.subject.kw | Asimetría hemisférica | es_ES |
dc.subject.ko | Resting state fMRI | es_ES |
dc.subject.ko | Default mode network | es_ES |
dc.subject.ko | Functional connectivity | es_ES |
dc.subject.ko | Grey matter volume | es_ES |
dc.subject.ko | Hemispheric asymmetry | es_ES |
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