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dc.creatorSaenger, Víctor M.
dc.creatorBarrios, Fernando A.
dc.creatorMartínez-Gudiño, María L.
dc.creatorAlcauter, Sarael
dc.date.accessioned2017-06-29T06:10:08Z
dc.date.available2017-06-29T06:10:08Z
dc.date.issued2012es_ES
dc.identifier715es_ES
dc.identifier.issn0028-3932es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/5399
dc.identifier.urihttps://doi.org/10.1016/j.neuropsychologia.2012.02.014es_ES
dc.language.isoenges_ES
dc.relation50 (7) 1308-1315 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleHemispheric asymmetries of functional connectivity and grey matter volume in the default mode networkes_ES
dc.typearticlees_ES
dc.contributor.affiliationUniversidad Nacional Autónoma de México, Facultad de Ciencias, Universidad 3000 Circuito Exterior S/N, C.P. 04510 Ciudad Universitaria, Mexicoes_ES
dc.contributor.emailsaenger@ciencias.unam.mxes_ES
dc.relation.jnabreviadoNEUROPSYCHOLOGIAes_ES
dc.relation.journalNeuropsychologiaes_ES
dc.identifier.placeOxfordes_ES
dc.date.published2012es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.doihttp://dx.doi.org/10.1016/j.neuropsychologia.2012.02.014es_ES
dc.description.monthJunes_ES
dc.description.abstractotrodiomaResting state networks such as the default mode network have been widely reported. Although a plethora of information on its functional relevance has been generated, little is known about lateralization or hemisphere asymmetry within the DMN. We used high-resolution resting state fMRI and T1 3D data to investigate such asymmetries in two groups of healthy subjects, one right-handed and one left-handed. Independent component analysis and the dual regression approach were carried out to identify functional asymmetries, while voxel-based morphometry was used to identify structural asymmetries in grey matter volume within the DMN. Greater leftward functional connectivity was observed in the posterior cingulate gyrus (PCG) for both groups. Leftward functional asymmetry was observed in the thalamus and rightward functional asymmetries were observed in the middle frontal and middle/superior temporal gyrus in the right-handed group. Rightward asymmetries in grey matter volume were observed in the posterior portion of the PCG for both groups. The right-handed group exhibited leftward structural asymmetries in the anterior portion of the PCG and in the middle frontal and posterior portion of the middle temporal gyrus, while rightward asymmetries were observed in the posterior portion of the PCG and anterior portions of temporal regions. These results suggest that functional connectivity and grey matter volume are not equally distributed between hemispheres within the DMN, and that functional asymmetries are not always reflected or determined by structural asymmetries.es_ES
dc.subject.kwEstado de reposo fMRIes_ES
dc.subject.kwModo de red Defaultes_ES
dc.subject.kwConectividad funcionales_ES
dc.subject.kwVolumen de materia grises_ES
dc.subject.kwAsimetría hemisféricaes_ES
dc.subject.koResting state fMRIes_ES
dc.subject.koDefault mode networkes_ES
dc.subject.koFunctional connectivityes_ES
dc.subject.koGrey matter volumees_ES
dc.subject.koHemispheric asymmetryes_ES


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