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Acute exercise reduces the effects of a 35% CO2 challenge in patients with panic disorder

dc.creatorEsquivel, Gabriel
dc.creatorDíaz-Galvis, John
dc.creatorSchruers, Koen
dc.creatorBerlanga, Carlos
dc.creatorLara-Muñoz, Carmen
dc.creatorGriez, Eric
dc.date.accessioned2017-06-29T06:02:59Z
dc.date.available2017-06-29T06:02:59Z
dc.date.issued2008es_ES
dc.identifier567es_ES
dc.identifier.issn0165-0327es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/5254
dc.identifier.urihttps://doi.org/10.1016/j.jad.2007.07.022es_ES
dc.language.isoenges_ES
dc.relation107 (1-3) 217-220 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdultes_ES
dc.subject.meshCarbon Dioxide-administration & dosagees_ES
dc.subject.meshCarbon Dioxide-diagnostic usees_ES
dc.subject.meshDiagnostic and Statistical Manual of Mental Disorderses_ES
dc.subject.meshExercise-physiologyes_ES
dc.subject.meshExercise Therapy-methodses_ES
dc.subject.meshFemalees_ES
dc.subject.meshHumanses_ES
dc.subject.meshLactates-bloodes_ES
dc.subject.meshMalees_ES
dc.subject.meshPanic Disorder-bloodes_ES
dc.subject.meshPanic Disorder-chemically inducedes_ES
dc.subject.meshPanic Disorder-prevention & controles_ES
dc.subject.meshPhysical Exertion-physiologyes_ES
dc.subject.meshPsychiatric Status Rating Scaleses_ES
dc.subject.meshTreatment Outcomees_ES
dc.titleAcute exercise reduces the effects of a 35% CO2 challenge in patients with panic disorderes_ES
dc.typearticlees_ES
dc.contributor.affiliationAcademic Anxiety Center, Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlandses_ES
dc.contributor.emailgabriel.esquivel@pn.unimaas.nles_ES
dc.relation.jnabreviadoJ AFFECT DISORDes_ES
dc.relation.journalJournal of Affective Disorderses_ES
dc.identifier.placeAmsterdames_ES
dc.date.published2008es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1573-2517es_ES
dc.identifier.doihttp://dx.doi.org/10.1016/j.jad.2007.07.022es_ES
dc.description.monthAbres_ES
dc.description.abstractotrodiomaBACKGROUND: Chronic exercise has been shown to have therapeutic effects in panic disorder (PD). The mechanism of these effects is unknown. Acute exercise reduces the effect of a panic challenge in healthy volunteers. Such an effect has not yet been demonstrated in PD patients. The present study aimed at exploring the antipanic effects of acute exercise on a 35% CO2 panic provocation in treatment-naïve PD patients to further elucidate the mechanisms of the beneficial effects of exercise on panic. METHODS: Eighteen PD patients performed either moderate-hard exercise or very-light exercise before a 35% CO2 challenge in a randomized, between-group design. The reactivity to CO2 was assessed with the Visual Analogue Anxiety Scale and the DSM-IV Panic Symptom List. RESULTS: Panic reactions to CO2 were smaller in patients that performed moderate-hard exercise in contrast to those that performed very-light exercise. Increments in both measurements and panic rates were consistently reduced by intense exercise. LIMITATIONS: Since this study focuses on the acute effects of exercise on CO2 sensitivity in patients with PD, the results of repetitive exercise sessions on the rate of spontaneous panic attacks and overall symptoms are warranted. The small sample size and other limitations are addressed. CONCLUSIONS: Exercise reduced the panicogenic effects of a CO2 challenge. In addition to its therapeutic potential, exercise may also be useful as a laboratory maneuver with heuristic value in experimental research into the mechanisms of antipanic treatment.es_ES
dc.subject.koPanic disorderes_ES
dc.subject.koExercisees_ES
dc.subject.koCarbon dioxidees_ES


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