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The P50 auditory evoked potential in violent and non-violent patients with schizophrenia

dc.creatorFresán, A
dc.creatorApiquian, R
dc.creatorGarcía-Anaya, M
dc.creatorde la Fuente-Sandoval, C
dc.creatorNicolini, H
dc.creatorGraff-Guerrero, A.
dc.date.accessioned2017-06-29T06:02:17Z
dc.date.available2017-06-29T06:02:17Z
dc.date.issued2007es_ES
dc.identifier537es_ES
dc.identifier.issn0920-9964es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/5224
dc.identifier.urihttps://doi.org/10.1016/j.schres.2007.09.017es_ES
dc.language.isoenges_ES
dc.relation97 (1-3) 128-136 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAcoustic stimulationes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAggression-Physiologyes_ES
dc.subject.meshArousal-Physiologyes_ES
dc.subject.meshCerebral cortex-Physiopathologyes_ES
dc.subject.meshElectroencephalographyes_ES
dc.subject.meshEvoked potentials, Auditory-Physiologyes_ES
dc.subject.meshFemalees_ES
dc.subject.meshHumanses_ES
dc.subject.meshMalees_ES
dc.subject.meshPsychiatric Status Rating Scaleses_ES
dc.subject.meshReaction time-Physiologyes_ES
dc.subject.meshReference valueses_ES
dc.subject.meshSchizophrenia-Diagnosises_ES
dc.subject.meshSchizophrenia-Physiopathologyes_ES
dc.subject.meshSchizophrenic Psychologyes_ES
dc.subject.meshSignal Processing, Computer-Assistedes_ES
dc.subject.meshViolence-Psychologyes_ES
dc.titleThe P50 auditory evoked potential in violent and non-violent patients with schizophreniaes_ES
dc.typearticlees_ES
dc.contributor.affiliationSubdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de Fuente, Mexico City, Mexicoes_ES
dc.relation.jnabreviadoSCHIZOPHR RESes_ES
dc.relation.journalSchizophrenia Researches_ES
dc.identifier.placePaíses bajoses_ES
dc.date.published2007es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1573-2509es_ES
dc.identifier.doi10.1016/j.schres.2007.09.017es_ES
dc.description.monthDices_ES
dc.description.abstractotrodiomaBACKGROUND: Emotionally driven violence is facilitated by increased arousal. It may be a consequence of an information-processing deficit and the cognitive attributions for the stimuli given by the subject. The aim of this study was to compare the P50 evoked potential responses of violent patients with schizophrenia with non-violent patients with schizophrenia and healthy controls. METHOD: Patients were classified into violent and non-violent in accordance to the Overt Aggression Scale. P50 auditory evoked potentials of 32 unmedicated patients with schizophrenia (violent=14, non-violent=18) and 17 healthy controls were recorded during five runs of 30 click pairs. RESULTS: Healthy controls exhibited a lower S2/S1 ratio when compared to violent (p<0.001) and non-violent (p=0.04) patients. Using a cutoff point of 0.50 for S2/S1 ratio to define abnormal gating a significant proportion of violent patients did not show P50 suppression (71.4%) in comparison to non-violent patients (38.9%) and healthy controls (23.5%) (p=0.02). CONCLUSIONS: Violent behavior in patients with schizophrenia could be associated with a disturbed information sensory gating. Violence in patients with schizophrenia may be facilitated by an increased arousal which may in turn be the result of an information-processing deficites_ES
dc.subject.kwEsquizofreniaes_ES
dc.subject.kwExcitaciónes_ES
dc.subject.kwP50 entrada auditivoes_ES
dc.subject.kwPotenciales evocadoses_ES
dc.subject.kwViolenciaes_ES
dc.subject.kwElectrofisiologíaes_ES
dc.subject.koSchizophreniaes_ES
dc.subject.koArousales_ES
dc.subject.koAuditory P50 gatinges_ES
dc.subject.koEvoked potentialses_ES
dc.subject.koViolencees_ES
dc.subject.koElectrophysiologyes_ES


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