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Altered microtubule associated proteins in schizophrenia

dc.creatorBenítez-King, Gloria
dc.creatorRamírez-Rodríguez, Gerardo
dc.creatorOrtíz-López, Leonardo
dc.date.accessioned2017-06-29T06:02:09Z
dc.date.available2017-06-29T06:02:09Z
dc.date.issued2007es_ES
dc.identifier529es_ES
dc.identifier.issn13035150es_ES
dc.identifier.urihttp://www.neuroquantology.com/index.php/journal/article/view/117/117es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/5216
dc.language.isoenges_ES
dc.relation5 (1) 58-61 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleAltered microtubule associated proteins in schizophreniaes_ES
dc.typearticlees_ES
dc.contributor.affiliationInstituto Nacional de Psiquiatría, Departamento de Neurofarmacología, Subdirección de Investigaciones Clínicas,México, D.F. Méxicoes_ES
dc.contributor.emailbekin@imp.edu.mxes_ES
dc.relation.jnabreviadoNEUROQUANTOLOGYes_ES
dc.relation.journalNeuroQuantologyes_ES
dc.date.published2007es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1303-5150es_ES
dc.description.monthMares_ES
dc.description.abstractotrodiomaIn schizophrenia, altered cognitive and affective functions as well as reduced dendritic spine density and diminished synaptic connectivity have been described. The cytoskeleton plays a key role in maintaining axon and dendrite structure as well as the synaptic connections. In this review we will describe evidence supporting that schizophrenia is a cytoskeletal disease. In addition, we will describe current data indicating that microtubule associated proteins are implicated in the abnormal dendrite structure and the lost of synaptic connectivity. Evidence presented here indicates that the cytoskeleton could be a target for drug therapy in shizophrenia.es_ES
dc.subject.kwEsquizofreniaes_ES
dc.subject.kwEnfermedad del citoesqueletoes_ES
dc.subject.kwProteínas asociadas a los microtúbuloses_ES
dc.subject.koSchizophreniaes_ES
dc.subject.koCytoskeletal diseasees_ES
dc.subject.koMicrotubule-associated proteinses_ES


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