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Electroencephalographic Responses to Alcohol Challenge in Native American Mission Indians

dc.creatorEhlers, Cindy L.
dc.creatorGarcía-Andrade, Consuelo
dc.creatorWall, Tamara L.
dc.creatorCloutier, David
dc.creatorPhillips, Evelyn
dc.date.accessioned2017-06-29T04:22:25Z
dc.date.available2017-06-29T04:22:25Z
dc.date.issued1999es_ES
dc.identifier280es_ES
dc.identifier.issn0006-3223es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4974
dc.identifier.urihttps://doi.org/10.1016/S0006-3223(98)00113-9es_ES
dc.language.isoenges_ES
dc.relation45 (6) 776-787 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdolescentes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAlcoholism-Diagnosises_ES
dc.subject.meshAlcoholism-Ethnologyes_ES
dc.subject.meshAlcoholism-Psychologyes_ES
dc.subject.meshBrain-Drug effectses_ES
dc.subject.meshElectroencephalographyes_ES
dc.subject.meshEthanol-Pharmacologyes_ES
dc.subject.meshHumanses_ES
dc.subject.meshIndians, North American-Psychologyes_ES
dc.subject.meshMalees_ES
dc.subject.meshRisk factorses_ES
dc.titleElectroencephalographic Responses to Alcohol Challenge in Native American Mission Indianses_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartment of Neuropharmacology, The Scripps Research Institute, La Jolla, Californiaes_ES
dc.relation.jnabreviadoBIOL PSYCHIATRYes_ES
dc.relation.journalBiological Psychiatryes_ES
dc.identifier.placeNew Yorkes_ES
dc.date.published1999es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1873-2402es_ES
dc.description.monthMares_ES
dc.description.abstractotrodiomaBACKGROUND: Native Americans have some of the highest rates of alcohol abuse and dependence, yet potential central nervous system risk factors responsible for the problem drinking seen in some tribes remain relatively unknown. METHODS: Background electroencephalographic (EEG) variants and response to alcohol were investigated in 48 Native American Mission Indian men between 18 and 25 years old. RESULTS: Subjects with 50% or greater Native American heritage had a significantly higher proportion of low-voltage EEG variants. Within this sample of Mission Indian men, however, a family history of alcohol dependence was associated with a greater incidence of high voltage alpha EEGs. Mission Indian men also evidenced a ‘less depressant, more stimulating’ response to alcohol as quantified by less alcohol-induced reductions in alpha, greater EEG stability, and increased alcohol-induced beta activity. CONCLUSIONS: These findings demonstrate that certain genetically regulated EEG variants that have been previously associated with risk for alcoholism in Caucasians may also be more common in these Mission Indian men. Additionally, EEG measures of response to alcohol do not provide support for the commonly held idea that Indians are more sensitive to the depressant effects of alcohol.es_ES
dc.subject.koElectroencephalographyes_ES
dc.subject.koNative Americanses_ES
dc.subject.koAlcohol dependencees_ES
dc.subject.koAlpha activityes_ES
dc.subject.koBeta activityes_ES
dc.subject.koEthanoles_ES


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