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dc.creatorGarcía-Andrade, C.
dc.creatorWall, T.L.
dc.creatorEhlers, C.L.
dc.date.accessioned2017-06-29T04:20:03Z
dc.date.available2017-06-29T04:20:03Z
dc.date.issued1997es_ES
dc.identifier238es_ES
dc.identifier.issn0002-953Xes_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4932
dc.identifier.urihttps://doi.org/10.1176/ajp.154.7.983es_ES
dc.language.isoenges_ES
dc.relation154 (7) 983-988 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdolescentes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAlcohol drinking-Bloodes_ES
dc.subject.meshAlcoholic intoxication-Bloodes_ES
dc.subject.meshAlcoholic intoxication-Etiologyes_ES
dc.subject.meshAlcoholic intoxication-Psychologyes_ES
dc.subject.meshAlcoholism-Geneticses_ES
dc.subject.meshBlood pressure-Drug effectses_ES
dc.subject.meshEthanol-Bloodes_ES
dc.subject.meshEthanol-Pharmacologyes_ES
dc.subject.meshGenetic Predisposition to Diseasees_ES
dc.subject.meshHumanses_ES
dc.subject.meshHydrocortisone-Bloodes_ES
dc.subject.meshIndians, North American-Geneticses_ES
dc.subject.meshIndians, North American-Psychologyes_ES
dc.subject.meshMalees_ES
dc.subject.meshPlaceboses_ES
dc.subject.meshPulse-Drug effectses_ES
dc.titleThe firewater myth and response to alcohol in Mission Indianses_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartment of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.es_ES
dc.relation.jnabreviadoAM J PSYCHIATRYes_ES
dc.relation.journalAmerican Journal of Psychiatryes_ES
dc.identifier.placeArlingtones_ES
dc.date.published1997es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1535-7228es_ES
dc.description.monthJules_ES
dc.description.abstractotrodiomaOBJECTIVE: This study aimed to assess empirically the intensity of reaction to alcohol in a group of Native Americans. METHOD: Forty healthy, nonalcoholic Mission Indian men between the ages of 18 and 25 years were tested before and after ingestion of placebo and 0.75 ml-kg of alcohol. Subjective (self-report of feelings) and objective (blood pressure, pulse rate, and plasma cortisol level) measures of intoxication were taken before ingestion of alcohol and placebo and at 15, 30, 60, 90, and 120 minutes after ingestion. Overall effects of alcohol were evaluated, and the responses of subjects with less than 50% Native American heritage (N = 19) were compared with the responses of subjects with at least 50% Native American heritage (N = 21). RESULTS: Alcohol did not produce any significant effects on any of the objective measures of intoxication; however, the subjects reported significant subjective effects of alcohol. Subjects with at least 50% Native American heritage reported less intense effects of alcohol than did those with less than 50% Native American heritage, despite equivalent blood alcohol concentrations. CONCLUSIONS: These results contradict the ‘firewater myth’--the theory that Native Americans are more sensitive to the effects of alcohol. Rather, the data indicate that Mission Indian men generally may be less sensitive to alcohol's effects, a physiological characteristic that has been shown to be associated with a greater risk for alcoholism in Caucasian populations. In addition, individuals with a greater percentage of Native American heritage may be less sensitive to the subjective effects of alcohol than individuals with a smaller percentage of Native American heritage.es_ES
dc.subject.kwAguardientees_ES
dc.subject.kwMitoes_ES
dc.subject.kwIndios de la misiónes_ES
dc.subject.kwAlcoholes_ES
dc.subject.kwNativos Americanoses_ES
dc.subject.koFirewateres_ES
dc.subject.koMythes_ES
dc.subject.koMission Indianses_ES
dc.subject.koAlcoholes_ES
dc.subject.koNative Americanses_ES


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