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DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder.

dc.creatorNicolini, H.
dc.creatorCruz, C.
dc.creatorCamarena, B.
dc.creatorOrozco, B.
dc.creatorKennedy, J.L.
dc.creatorKing, N.
dc.creatorWeissbecker, K.
dc.creatorDe la Fuente, J.R.
dc.creatorSidenberg, D.
dc.date.accessioned2017-06-29T04:19:40Z
dc.date.available2017-06-29T04:19:40Z
dc.date.issued1996es_ES
dc.identifier230es_ES
dc.identifier.issn1359-4184es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4924
dc.language.isoenges_ES
dc.relation1 (6) 461-465 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleDRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder.es_ES
dc.typearticlees_ES
dc.contributor.affiliationDivisión de Investigaciones Clínicas, Instituto Mexicano de Psiquiatria, México, México DF.es_ES
dc.relation.jnabreviadoMOL PSYCHIATRYes_ES
dc.relation.journalMolecular psychiatryes_ES
dc.identifier.placeEnglandes_ES
dc.date.published1996es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.description.monthDices_ES
dc.description.abstractotrodiomaWe performed an association analysis of the DRD2, DRD3 and 5HT2A genes polymorphisms in 67 Obsessive-Compulsive Disorder (OCD) patients and 54 healthy controls. There were no statistically significant differences in genotype or allele frequencies for any of the polymorphisms studied between OCD subjects and controls. For the subgrouped analysis, no results were significant after correction for multiple testing, although homozygosity of DRD2/A2A2 in subjects displaying vocal or motor tics approached significance compared to controls (Fisher exact test, P = 0.008). Our results may follow the notion that OCD patients with tics represent a different genetic subtype of the disease.es_ES


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