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In vitro release of immunoreactive Met- and Leu-enkephalins in whole perioesophageal ganglia of Helix aspersa

dc.creatorPellicer, F.
dc.creatorAsai, M.
dc.creatorLeón-Olea, M.
dc.creatorSánchez-Álvarez, M.
dc.date.accessioned2017-06-29T04:16:27Z
dc.date.available2017-06-29T04:16:27Z
dc.date.issued1993es_ES
dc.identifier155es_ES
dc.identifier.issn0742-8413es_ES
dc.identifier.urihttp://dx.doi.org/10.1016/0742-8413(93)90042-Jes_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4849
dc.language.isoenges_ES
dc.relation104 (2) 323-325 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleIn vitro release of immunoreactive Met- and Leu-enkephalins in whole perioesophageal ganglia of Helix aspersaes_ES
dc.typearticlees_ES
dc.contributor.affiliationDivisión de Neurociencias, Instituto Mexicano de Psiquiatria, México, DFes_ES
dc.relation.jnabreviadoCOMP BIOCHEM PHYSIOL Ces_ES
dc.relation.journalComparative Biochemistry and Physiology Part C: Comparative Pharmacologyes_ES
dc.identifier.placeInglaterraes_ES
dc.date.published1993es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.doi10.1016/0742-8413(93)90042-Jes_ES
dc.description.monthFebes_ES
dc.description.abstractotrodioma1. The release mechanism of immunoreactive Met- and Leu-enkephalins was studied by radioimmunoassay (RIA) with highly specific antisera in whole perioesophageal ganglia of the snail Helix aspersa. 2. The release was measured under three different experimental situations: (a) basal release, (b) during a high potassium depolarizing pulse and (c) without Ca2+.3. Our results show that IR-ME-IR-LE ratio, under a high potassium depolarizing pulse, was approximately 2:1. The release mechanism for enkephalins is enhanced by a depolarizing pulse and is Ca2+ dependent. 4. This preparation provides a good model to investigate physiological or pathological conditions in which opioid peptides are involved.es_ES
dc.subject.kwEncefalina metioninaes_ES
dc.subject.kwEncefalina leucinaes_ES
dc.subject.kwLiberaciónes_ES
dc.subject.kwGanglio nerviosoes_ES
dc.subject.kwIn vitroes_ES
dc.subject.kwMétodo radioinmunológicoes_ES
dc.subject.kwPéptido opioidees_ES
dc.subject.kwNeuropéptidoes_ES
dc.subject.kwSistema nerviosoes_ES
dc.subject.kwHelix aspersaes_ES
dc.subject.kwGastropodaes_ES
dc.subject.kwMolluscaes_ES
dc.subject.kwInvertebrataes_ES
dc.subject.koMethionine enkephalines_ES
dc.subject.koLeucine enkephalines_ES
dc.subject.koReleasees_ES
dc.subject.koNervous gangliones_ES
dc.subject.koIn vitroes_ES
dc.subject.koRadioimmunoassayes_ES
dc.subject.koOpioid peptidees_ES
dc.subject.koNeuropeptidees_ES
dc.subject.koNervous systemes_ES
dc.subject.koHelix aspersaes_ES
dc.subject.koGastropodaes_ES
dc.subject.koMolluscaes_ES
dc.subject.koInvertebrataes_ES


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