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Participation of the GABA-benzodiazepine system in the inhibition of defensive burying produced by ejaculation

dc.creatorFernández-Guasti, A.
dc.creatorSaldívar, A.
dc.date.accessioned2017-06-29T04:14:34Z
dc.date.available2017-06-29T04:14:34Z
dc.date.issued1990es_ES
dc.identifier92es_ES
dc.identifier.issn0955-8810es_ES
dc.identifier.urihttp://journals.lww.com/behaviouralpharm/Abstract/1990/00150/Participation_of_the_GABA_benzodiazepine_system_in.4.aspxes_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4787
dc.language.isoenges_ES
dc.relation1 (5) 429-436 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleParticipation of the GABA-benzodiazepine system in the inhibition of defensive burying produced by ejaculationes_ES
dc.typearticlees_ES
dc.contributor.affiliationSección de Terapéutica Experimental, Departamento de Farmacología y Toxicología, CINVESTAV, México D.F., and División de Investigaciones en Neurociencias, Insituto Mexicano de Psiquiatria, México D.F., Méxicoes_ES
dc.relation.jnabreviadoBEHAV PHARMACOLes_ES
dc.relation.journalBehavioural Pharmacologyes_ES
dc.identifier.placeInglaterraes_ES
dc.date.published1990es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1473-5849es_ES
dc.description.monthOtoñes_ES
dc.description.abstractotrodiomaWe recently reported a reduction in defensive burying behaviour after ejaculation. The present study analyzed whether this reduction was mediated via an increase in GABAergic transmission. Two experimental series were included: in the first series the reduction in burying behaviour was blocked by Ro 15-1788 (5 and 10 mg-kg), bicuculline (2.5 mg-kg) and picrotoxin (0.5 mg-kg). In the second series the effect of ejaculation on defensive burying was potentiated by diazepam (0.5 mg-kg) or muscimol (0.5 mg-kg). With the exception of 10 mg-kg of Ro 15-1788 these treatments did not affect the basal burying behaviour levels. The results support the hypothesis that the GABA-benzodiazepine system participates in the reduction in burying behaviour found after ejaculation, and are discussed on the basis of neurochemical and pharmacological data indicating an increase in GABAergic transmission during the postejaculatory intervales_ES
dc.subject.koDefensive buryinges_ES
dc.subject.koEjaculationes_ES
dc.subject.koGABAes_ES
dc.subject.koRo 15-1788es_ES
dc.subject.koBicucullinees_ES
dc.subject.koPicrotoxines_ES
dc.subject.koMuscimoles_ES
dc.subject.koDiazepames_ES


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