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Evidence for the involvement of central 5-HT1A receptors in the mediation of lordosis behavior in the female rat

dc.creatorAhlenius, Sven
dc.creatorLarsson, Knut
dc.creatorFernández-Guasti, Alonso
dc.date.accessioned2017-06-29T04:14:27Z
dc.date.available2017-06-29T04:14:27Z
dc.date.issued1989es_ES
dc.identifier87es_ES
dc.identifier.issn0033-3158es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4782
dc.identifier.urihttps://doi.org/10.1007/BF00441938es_ES
dc.language.isoenges_ES
dc.relation98 (4) 440-444 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleEvidence for the involvement of central 5-HT1A receptors in the mediation of lordosis behavior in the female rates_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartment of Psychology, University of Göteborg, Swedenes_ES
dc.relation.jnabreviadoPSYCHOPHARMACOLOGYes_ES
dc.relation.journalPsychopharmacologyes_ES
dc.identifier.placeAlemaniaes_ES
dc.date.published1989es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1432-2072es_ES
dc.description.monthAgoes_ES
dc.description.abstractotrodioma5-Hydroxy-L-tryptophan (5-HTP), 25 mg kg-1 IP, in combination with the peripheral 5-HTP decarboxylase inhibitor benserazide, 25 mg kg-1 IP, and the selective inhibitor of neuronal 5-hydroxytryptamine (5-HT) re-uptake, zimeldine, 10 mg kg-1 IP, suppressed lordosis in ovariectomized female rats, treated with estradiol benzoate (EB) or with EB plus progesterone (P). The suppression of lordosis produced by 5-HTP was antagonized by the beta-receptor blocker (-)pindolol, which also is a selective 5-HT1 receptor antagonist, but not by the 5-HT2 receptor antagonists metitepine or pirenperone, nor by the beta-receptor blocker betaxolol. The EB- or EB plus P-activated lordosis was also suppressed by administration of the selective 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Together, these observations indicate an important role of central 5-HT1A receptors in the mediation of lordosis behavior in the female rat.es_ES
dc.subject.ko5-Hydroxytryptophan-Pharmacologyes_ES
dc.subject.ko8-Hydroxy-2-(di-n-propylamino)tetralines_ES
dc.subject.koAnimalses_ES
dc.subject.koBetaxololes_ES
dc.subject.koEstradiol-Pharmacologyes_ES
dc.subject.koFemalees_ES
dc.subject.koMalees_ES
dc.subject.koMethiothepin-Pharmacology]es_ES
dc.subject.koPindolol-Pharmacologyes_ES
dc.subject.koPiperidines-Pharmacologyes_ES
dc.subject.koPosturees_ES
dc.subject.koPropanolamines-Pharmacologyes_ES
dc.subject.koRatses_ES
dc.subject.koRats, Inbred Strainses_ES
dc.subject.koReceptors, Serotonin-Drug Effectses_ES
dc.subject.koReceptors, Serotonin-Physiologyes_ES
dc.subject.koSexual Behavior, Animal-Drug Effectses_ES
dc.subject.koSexual Behavior, Animal-Physiologyes_ES
dc.subject.koTetrahydronaphthalenes-Pharmacologyes_ES


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