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The effect of temperature on electrical interactions between antidromically stimulated frog motoneurons and dorsal root afferent axons

dc.creatorCruzblanca, H.
dc.creatorAlvarez-Leefmans, F.J.
dc.date.accessioned2017-06-29T04:14:24Z
dc.date.available2017-06-29T04:14:24Z
dc.date.issued1989es_ES
dc.identifier85es_ES
dc.identifier.issn0306-4522es_ES
dc.identifier.urihttp://dx.doi.org/10.1016/0306-4522(89)90321-7es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4780
dc.language.isoenges_ES
dc.relation33 (1) 193-201 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleThe effect of temperature on electrical interactions between antidromically stimulated frog motoneurons and dorsal root afferent axonses_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartamento de Neurobiología, División de Neurociencias, Instituto Mexicano de Psiquiatría, México, 14370, D.F.es_ES
dc.relation.jnabreviadoNEUROSCIENCEes_ES
dc.relation.journalNeurosciencees_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published1989es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1873-7544es_ES
dc.identifier.doi10.1016/0306-4522(89)90321-7es_ES
dc.description.abstractotrodiomaThe effect of temperature on electrical interactions between antidromically stimulated motoneruons and dorsal root afferents was studied in the isolated and hemisected spinal cord of the frog, superfused with Ringer in which Ca2+ was equimolarly replaced by Co2+ or Mn2+ to suppress chemical synaptic transmission. Suction electrodes were used for stimulating and-or recorcling from dorsal and ventral roots from segments IX or X. Intrafibre recorclings from sensory fibres were made at their point of entry into the spinal cord. Supramaximal ventral root stimuli elicited two distinct responses in the segmental dorsal root. First a brief short-latency depolarizing potential. Second, at temperatures below 11°C, a second depolarizing root potential appeared following the short-latency depolarizing potential-I. Amplitude and duration of short-latency depolarizing potential-II reversibly increased as the bath temperature was decreased, reaching a maximum at 3°C. Between 8 and 3°C, short-latency depolarizing potential-II increased in amplitude by 20%-°C. In contrast short-latency depolarizing potential-I did not show substantial changes with temperature. The short-latency depolarizing potential-II, unlike shortlatency depolarizing potential-I showed stepped fluctuations in amplitude, and appeared to be composed of unitary events. Intrafibre records revealed that the unitary events corresponded to action potentials on individual dorsal root fibres. Double shocks applied to the ventral root, at constant bath temperatures (below 11°C), revealed facilitation of the short-latency depolarizing potential-II, which was maximal between 50 and 80 ms and lasted about 200 ms. Neither the antidromic motoneurone field potential nor the short-latency depolarizing potential-I were facilitated. The results show that the short-latency depolarizing potential-II reflects the relatively synchronous antidromic firing of action potentials in some sensory axons in response to ventral root stimuli. It is proposed that the short-latency depolarizing potential-II results from electrical coupling between some afferent terminals encling monosynaptically on distal motoneuron dendrites. The unmasking and apparent enhancement of electrical coupling when lowering the temperature is likely to result from changes in the electrical properties of non-junctional membranes.es_ES
dc.subject.meshmACh, acetylcholinees_ES
dc.subject.meshm4-AP, 4-aminopyridinees_ES
dc.subject.meshmAPs, action potentialses_ES
dc.subject.meshmDR, dorsal rootes_ES
dc.subject.meshmDRPs, dorsal root potentialses_ES
dc.subject.meshmHEPES, N-2-hydroxyethylpiperazine-N_-2-ethane sulphonic acides_ES
dc.subject.meshmMN FP, antidromic motoneuron field potential evoked by VR stimulus and recorded in the motor nucleuses_ES
dc.subject.meshmVR, ventral rootes_ES
dc.subject.meshmVR-DRP, dorsal root potential elicited by ventral root stimuluses_ES
dc.subject.kwPotenciales de acciónes_ES
dc.subject.kwAnimaleses_ES
dc.subject.kwEstimulación eléctricaes_ES
dc.subject.kwMotor de neuronas-Fisiologíaes_ES
dc.subject.kwNeuronas aferentes-Fisiologíaes_ES
dc.subject.kwRana pipienses_ES
dc.subject.kwRánidos-Fisiologíaes_ES
dc.subject.kwRaíces nerviosas de la columna-Fisiologíaes_ES
dc.subject.kwTemperaturaes_ES
dc.subject.koAction potentialses_ES
dc.subject.koAnimalses_ES
dc.subject.koElectric stimulationes_ES
dc.subject.koNeurons, afferent-Physiologyes_ES
dc.subject.koMotor neurons-Physiologyes_ES
dc.subject.koRana pipienses_ES
dc.subject.koRanidae-Physiologyes_ES
dc.subject.koTemperaturees_ES
dc.subject.koSpinal nerve roots-Physiologyes_ES


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