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Dorsal raphe and nociceptive stimulations evoke convergent responses on the thalamic centralis lateralis and medial prefrontal cortex neurons

dc.creatorCondés-Lara, Miguel
dc.creatorOmaña Zapata, Imelda
dc.creatorLeón-Olea, Martha
dc.creatorSánchez-Álvarez, Marcela
dc.date.accessioned2017-06-29T04:14:12Z
dc.date.available2017-06-29T04:14:12Z
dc.date.issued1989es_ES
dc.identifier76es_ES
dc.identifier.issn0006-8993es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4771
dc.language.isoenges_ES
dc.relation499 (1) 145-152 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleDorsal raphe and nociceptive stimulations evoke convergent responses on the thalamic centralis lateralis and medial prefrontal cortex neuronses_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartamento de Neurofisiología, lnstituto Mexicano de Psiquiatría, Méxicoes_ES
dc.relation.jnabreviadoBRAIN RESes_ES
dc.relation.journalBrain researches_ES
dc.identifier.placeAmsterdam, Holandaes_ES
dc.date.published1989es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.description.monthOctes_ES
dc.description.abstractotrodiomaThere is evidence for the existence of a descending pain suppression system, but also there are data supporting the hypothesis for the modulation of pain at higher central nervous system levels. In the present study we give evidence for a possible ascending pain modulation pathway which involves the dorsal raphe (DR), the centralis lateralis nucleus (CL) of the thalamus and the medial prefrontal cortex (PFCx). Urethane-anesthetized rats were used. Simultaneous single unit recordings were done in the CL and PFCx regions under noxious and DR stimulations. Cells responding to both types of stimuli exhibit duration responses directly related to the duration of the stimuli. Thus, from our results we conclude a DR influence upon CL and PFCx structures that are involved in the coding of nociceptive information. A possible route for an ascending pain modulation path is proposed.es_ES
dc.subject.kwNocicepcióncorteza prefrontal mediales_ES
dc.subject.kwNúcleo lateral centrales_ES
dc.subject.kwNúcelo dorsal de rafées_ES
dc.subject.kwModulación ascendente del dolores_ES
dc.subject.kwTrayectoriaes_ES
dc.subject.kwRatases_ES
dc.subject.koNociceptiones_ES
dc.subject.koMedial prefrontal cortexes_ES
dc.subject.koCentralis lateralis nucleuses_ES
dc.subject.koDorsal raphe nucleuses_ES
dc.subject.koAscending paines_ES
dc.subject.kopathwayes_ES
dc.subject.koRatmodulationes_ES


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