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Psychopharmacologic analysis of an alleged oneirogenic plant: Calea zacatechichi

dc.creatorMayagoitia, Lilian
dc.creatorDíaz, José-Luis
dc.creatorContreras, Carlos M.
dc.date.accessioned2017-06-29T04:13:41Z
dc.date.available2017-06-29T04:13:41Z
dc.date.issued1986es_ES
dc.identifier47es_ES
dc.identifier.issn0378-8741es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4742
dc.language.isoenges_ES
dc.relation18 (3) 229-243 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titlePsychopharmacologic analysis of an alleged oneirogenic plant: Calea zacatechichies_ES
dc.typearticlees_ES
dc.contributor.affiliationDepartamento de Psicología y Conducta, Instituto Mexicano de Psiquiatría, antiguo Camino a Xochimilco 101, San Lorenzo Huipulco, Tlalpan 14370 and Departamento de Fisiología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, apartado Postal 70228, Ciudad Universitaria, Coyoacan 04510 (México, D.F)es_ES
dc.relation.jnabreviadoJ ETHNOPHARMACOLes_ES
dc.relation.journalJournal of Ethnopharmacologyes_ES
dc.identifier.placeIrlandaes_ES
dc.date.published1986es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.identifier.eissn1872-7573es_ES
dc.description.monthDices_ES
dc.description.abstractotrodiomaCalea zacatechichi is a plant used by the Chontal Indians of Mexico to obtain divinatory messages during dreaming. At human doses, organic extracts of the plant produce the EEG and behavioral signs of somnolence and induce light sleep in cats. Large doses elicit salivation, ataxia, retching and occasional vomiting. The effects of the plant upon cingulum discharge frequency were significantly different from hallucinogenic-dissociative drugs (ketamine, quipazine, phencyclidine and SKF-10047). In human healthy volunteers, low doses of the extracts administered in a double-blind design against placebo increased reaction time and time-lapse estimation. A controlled nap sleep study in the same volunteers showed that Calea extracts increased the superficial stages of sleep and the number of spontaneous awakenings. The subjective reports of dreams were significantly higher than both placebo and diazepam, indicating an increase in hypnagogic imagery occurring during superficial sleep stages.es_ES
dc.subject.koAdultes_ES
dc.subject.koAnalysis of Variancees_ES
dc.subject.koAnimalses_ES
dc.subject.koBehavior, Animal-Drug Effectses_ES
dc.subject.koCatses_ES
dc.subject.koDiazepam-Pharmacologyes_ES
dc.subject.koDouble-Blind Methodes_ES
dc.subject.koDreams-Drug effectses_ES
dc.subject.koElectroencephalographyes_ES
dc.subject.koFemalees_ES
dc.subject.koHumanses_ES
dc.subject.koMalees_ES
dc.subject.koMexicoes_ES
dc.subject.koPlant Extracts-Pharmacologyes_ES
dc.subject.koPlants, Medicinales_ES
dc.subject.koPsychotropic Drugses_ES
dc.subject.koRandom Allocationes_ES
dc.subject.koReaction Time-Drug effectses_ES
dc.subject.koRespiration-Drug effectses_ES
dc.subject.koSleep-Drug effectses_ES
dc.subject.koTime Perception-Drug effectses_ES


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