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Effects of clonidine in narcolepsy

dc.creatorSalín-Pascual, R.
dc.creatorDe la Fuente, J.R.
dc.creatorFernández-Guardiola, A.
dc.date.accessioned2017-06-29T04:13:38Z
dc.date.available2017-06-29T04:13:38Z
dc.date.issued1985es_ES
dc.identifier44es_ES
dc.identifier.issn0160-6689es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4739
dc.language.isoenges_ES
dc.relation46 (12) 528-531 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdultes_ES
dc.subject.meshClonidinees_ES
dc.subject.meshPharmacologyes_ES
dc.subject.meshTherapeutic usees_ES
dc.subject.meshDrug Evaluationes_ES
dc.subject.meshElectroencephalographyes_ES
dc.subject.meshFemalees_ES
dc.subject.meshHumanses_ES
dc.subject.meshMalees_ES
dc.subject.meshMiddle Agedes_ES
dc.subject.meshNarcolepsyes_ES
dc.subject.meshDrug therapyes_ES
dc.subject.meshPsychologyes_ES
dc.subject.meshSleepes_ES
dc.subject.meshDrug effectes_ES
dc.subject.meshSleep, REMes_ES
dc.subject.meshDrug effectses_ES
dc.titleEffects of clonidine in narcolepsyes_ES
dc.typearticlees_ES
dc.relation.jnabreviadoJ CLIN PSYCHIATRYes_ES
dc.relation.journalJournal of Clinical Psychiatryes_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published1985es_ES
dc.identifier.organizacionInstituto Mexicano de Psiquiatríaes_ES
dc.description.monthDices_ES
dc.description.abstractotrodiomaThe antihypertensive drug clonidine was given in an open trial to two treatment-resistant (psychostimulants and tricyclic antidepressants) narcoleptic patients. When given acutely, clonidine suppressed REM sleep. However, patients became tolerant after repeated doses but did not lose the drug's beneficial clinical effects. This suggests that REM suppression may not be necessary for improvement in narcolepsy. Assessments of both clinical and polysomnographic variables before and after the trial indicate that clonidine may have a place in the treatment of some patients with narcolepsy.es_ES


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