Mostrar el registro sencillo del ítem
Internet gaming and addiction: a reply to King & Delfabbro
dc.creator | Petry, N. M. | |
dc.creator | Rehbein, F. | |
dc.creator | Gentile, D. A. | |
dc.creator | Lemmens, J. S. | |
dc.creator | Rumpf, H. J. | |
dc.creator | Mossle, T. | |
dc.creator | Bischof, G. | |
dc.creator | Tao, R. | |
dc.creator | Fung, D. S. S. | |
dc.creator | Borges, G. | |
dc.creator | Auriacombe, M. | |
dc.creator | Gonzalezibanez, A. | |
dc.creator | Tam, P. | |
dc.creator | O'Brien, C. P. | |
dc.date.accessioned | 2017-06-29T03:54:39Z | |
dc.date.available | 2017-06-29T03:54:39Z | |
dc.date.issued | 2014 | es_ES |
dc.identifier | 2776 | es_ES |
dc.identifier.issn | 0965-2140 | es_ES |
dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/4625 | |
dc.identifier.uri | https://doi.org/10.1111/add.12549 | es_ES |
dc.description.abstract | es_ES | |
dc.language.iso | eng | es_ES |
dc.publisher | Oxford : Wiley-Blackwell | es_ES |
dc.relation | 109 (9) 1567-1568 p. | es_ES |
dc.relation | versión del editor | es_ES |
dc.rights | acceso cerrado | es_ES |
dc.subject.mesh | Behavior, Addictive/diagnosis | es_ES |
dc.subject.mesh | Consensus | es_ES |
dc.subject.mesh | Diagnostic and Statistical Manual of Mental Disorders | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Internationality | es_ES |
dc.subject.mesh | Video Games/psychology | es_ES |
dc.title | Internet gaming and addiction: a reply to King & Delfabbro | es_ES |
dc.title.alternative | es_ES | |
dc.type | artículo | es_ES |
dc.contributor.affiliation | University of Connecticut School of Medicine, Farmington, CT, USA. | es_ES |
dc.contributor.email | npetry@uchc.edu | es_ES |
dc.relation.jnabreviado | ADDICTION | es_ES |
dc.relation.journal | Addiction | es_ES |
dc.identifier.place | Inglaterra | es_ES |
dc.date.published | 2014 | es_ES |
dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | es_ES |
dc.identifier.eissn | 1360-0443 | es_ES |
dc.identifier.doi | 10.1111/add.12549 | es_ES |
dc.description.month | Sep | es_ES |
dc.description.abstractotrodioma | OBJECTIVE: Second-generation antipsychotics (SGAs) are among the first-line treatments for bipolar disorder and schizophrenia, but have a tendency to generate metabolic disturbances. These features resemble a metabolic syndrome for which a central autonomic imbalance has been proposed that may originate from the hypothalamic suprachiasmatic nuclei. In a clinical trial, we hypothesized that melatonin, a hormone that regulates the suprachiasmatic nucleus, could attenuate SGA-induced adverse metabolic effects. METHODS: In an eight-week, double-blind, randomized, placebo-controlled, parallel-group clinical trial, we evaluated the metabolic effect of melatonin in SGA-treated patients in terms of weight, blood pressure, lipid, glucose, body composition, and anthropometric measures. A total of 44 patients treated with SGAs, 20 with bipolar disorder and 24 with schizophrenia, randomly received placebo (n = 24) or melatonin 5 mg (n = 20). RESULTS: The melatonin group showed a decrease in diastolic blood pressure (5.1 versus 1.1 mmHg for placebo, p = 0.003) and attenuated weight gain (1.5 versus 2.2 kg for placebo, F = 4.512, p = 0.040) compared to the placebo group. The strong beneficial metabolic effects of melatonin in comparison to placebo on fat mass (0.2 versus 2.7 kg, respectively, p = 0.032) and diastolic blood pressure (5.7 versus 5.5 mmHg, respectively, p = 0.001) were observed in the bipolar disorder and not in the schizophrenia group. No adverse events were reported. CONCLUSIONS: Our results show that melatonin is effective in attenuating SGAs' adverse metabolic effects, particularly in bipolar disorder. The clinical findings allow us to propose that SGAs may disturb a centrally mediated metabolic balance that causes adverse metabolic effects and that nightly administration of melatonin helps to restore. Melatonin could become a safe and cost-effective therapeutic option to attenuate or prevent SGA metabolic effects. | es_ES |
dc.subject.meshm | es_ES | |
dc.subject.kw | es_ES | |
dc.subject.ko | Addiction | es_ES |
dc.subject.ko | Behavioral Addiction | es_ES |
dc.subject.ko | Diagnosis | es_ES |
dc.subject.ko | Gambling Disorders | es_ES |
dc.subject.ko | Internet Gaming | es_ES |
dc.subject.ko | Treatment | es_ES |