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IL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patients

dc.creatorMendieta, Danelia
dc.creatorDe la Cruz-Aguilera, Dora Luz
dc.creatorBarrera-Villalpando, Maria Isabel
dc.creatorBecerril-Villanueva, Enrique
dc.creatorArreola, Rodrigo
dc.creatorHernández-Ferreira, Erick
dc.creatorPérez-Tapia, Sonia Mayra
dc.creatorPérez-Sánchez, Gilberto
dc.creatorGarcés-Alvarez, María Eugenia
dc.creatorAguirre-Cruz, Lucinda
dc.creatorVelasco-Velázquez, Marco Antonio
dc.creatorPavón, Lenin
dc.date.accessioned2017-06-29T03:53:19Z
dc.date.available2017-06-29T03:53:19Z
dc.date.issued2016es_ES
dc.identifier2760es_ES
dc.identifier.issn0165-5728es_ES
dc.identifier.urihttp://dx.doi.org/10.1016/j.jneuroim.2015.11.011es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4609
dc.language.isoenges_ES
dc.publisher[Amsterdam] : Elsevier/North-Hollandes_ES
dc.relation290, 22-25 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleIL-8 and IL-6 primarily mediate the inflammatory response in fibromyalgia patientses_ES
dc.typeartículoes_ES
dc.contributor.affiliationClinical Service, National Institute of Psychiatry “Ramón de la Fuente”, Calzada México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, 14370 Mexico City, DF, Mexicoes_ES
dc.contributor.emaildanemend@hotmail.com, cruza_dl@hotmail.com, maribel_barrerav@yahoo.com.mxes_ES
dc.relation.jnabreviadoJ NEUROIMMUNOLes_ES
dc.relation.journalJournal of Neuroimmunologyes_ES
dc.identifier.placePaíses Bajoses_ES
dc.date.published2016es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1872-8421es_ES
dc.identifier.doi10.1016/j.jneuroim.2015.11.011es_ES
dc.description.abstractotrodiomaFibromyalgia (FM)is a chronic disease that has been linked to inflammatory reactions and changes in the systemic levels of proinflammatory cytokines that modulate responses in the sympathetic nervous system and hypothalamic-pituitary-adrenal axis. We found that concentrations of IL-6 and IL-8were elevated in FM patients. Both cytokines correlated with clinical scores, suggesting that IL-6 and IL-8 have additive or synergistic effects in perpetuating the chronic pain in FM patients. These findings indicate that IL-6 and IL-8 are two of the most constant inflammatory mediators in FM and that their levels correlate significantly with the severity of symptomses_ES
dc.subject.koFibromyalgiaes_ES
dc.subject.koIL-6es_ES
dc.subject.koIL-8es_ES
dc.subject.koFIQes_ES
dc.subject.koInflammationes_ES


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