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dc.creatorFlores-Ramos, Mónica
dc.creatorMoreno, Julia
dc.creatorHeinze, Gerhard
dc.creatorAguilera-Pérez, Rafael
dc.creatorPellicer Graham, Francisco
dc.date.accessioned2017-06-29T03:51:45Z
dc.date.available2017-06-29T03:51:45Z
dc.date.issued2014es_ES
dc.identifier2740es_ES
dc.identifier.issn0951-3590es_ES
dc.identifier.urihttp://dx.doi.org/10.3109/09513590.2013.875994es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4589
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisherLondon : Informa Healthcarees_ES
dc.relation30 (3) 232-235 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAnxiety-Etiologyes_ES
dc.subject.meshAnxiety-Physiopathologyes_ES
dc.subject.meshBlood Platelets-Metabolismes_ES
dc.subject.meshDepression-Bloodes_ES
dc.subject.meshDepression-Etiologyes_ES
dc.subject.meshDepression-Physiopathologyes_ES
dc.subject.meshDepressive Disorder-Etiologyes_ES
dc.subject.meshDepressive Disorder-Physiopathologyes_ES
dc.subject.meshDiagnostic and Statistical Manual of Mental Disorderses_ES
dc.subject.meshFemalees_ES
dc.subject.meshGonadal Hormones-Bloodes_ES
dc.subject.meshHot Flashes-Etiologyes_ES
dc.subject.meshHot Flashes-Physiopathologyes_ES
dc.subject.meshHumanses_ES
dc.subject.meshMexicoes_ES
dc.subject.meshMiddle Agedes_ES
dc.subject.meshPerimenopause-Bloodes_ES
dc.subject.meshPerimenopause-Psychologyes_ES
dc.subject.meshPsychiatric Status Rating Scaleses_ES
dc.subject.meshSelf Reportes_ES
dc.subject.meshSerotonin-bloodes_ES
dc.subject.meshSeverity of Illness Indexes_ES
dc.subject.meshSleep Initiation and Maintenance Disorders-Etiologyes_ES
dc.subject.meshSleep Initiation and Maintenance Disorders-Physiopathologyes_ES
dc.subject.meshSleep Initiation and Maintenance Disorders-Psychologyes_ES
dc.subject.meshTryptophan-Bloodes_ES
dc.titleGonadal hormone levels and platelet tryptophan and serotonin concentrations in perimenopausal women with or without depressive symptomses_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationDepartment of Neurosciences, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Distrito Federal, Mexicoes_ES
dc.contributor.emailflores_ramos@hotmail.comes_ES
dc.relation.jnabreviadoGYNECOL ENDOCRINOLes_ES
dc.relation.journalGynecological Endocrinologyes_ES
dc.identifier.placeInglaterraes_ES
dc.date.published2014es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1473-0766es_ES
dc.identifier.doi10.3109/09513590.2013.875994es_ES
dc.description.monthMares_ES
dc.description.abstractotrodiomaIntroduction: The etiology of depressive symptoms associated with the transition to menopause is still unknown; hormonal changes, serotonergic system or insomnia, could be a trigger to depressive symptomatology. The aim of the present study was to evaluate gonadal hormonal levels, platelet serotonin concentrations and platelet tryptophan concentrations in a group of depressed perimenopausal women and their healthy counterparts. Methods: A total of 63 perimenopausal women between 45 and 55 years old were evaluated; of these, 44 were depressed patients, and 19 were perimenopausal women without depression. The instruments that were applied included the Center for Epidemiologic Studies Depression Scale (CES-D), the Hamilton Depression Rating Scale (HDRS) and the Green Climacteric Scale (GCS); gonadal hormone levels and platelet tryptophan and serotonin concentrations were measured in all participants. Differences in hormonal levels and tryptophan and serotonin concentrations were evaluated with respect to specific symptoms, such as insomnia, hot flashes, nervousness, depressed mood and loss of interest. Results: No differences between groups were observed with respect to hormonal levels and tryptophan and serotonin concentrations; mean sleep hours and insomnia were significantly correlated with platelet tryptophan concentrations. Conclusions: In this sample, all symptoms of depression could not be explained by platelet tryptophan and serotonin concentrations and hormonal levels; differences were observed only when we evaluated insomnia and hot flashes.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koDepressive disorderes_ES
dc.subject.koGonadal hormoneses_ES
dc.subject.koPerimenopausees_ES
dc.subject.koTryptophanes_ES


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