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dc.creatorGlobal Burden of Disease Study 2013 Collaborators
dc.creatorBenjet C.
dc.creatorGutiérrez RA
dc.creatorBorges, G
dc.date.accessioned2017-06-29T03:51:34Z
dc.date.available2017-06-29T03:51:34Z
dc.date.issued2015es_ES
dc.identifier2738es_ES
dc.identifier.issn0140-6736es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4587es_ES
dc.identifier.urihttp://dx.doi.org/10.1016/S0140-6736(15)60692-4es_ES
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561509/es_ES
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisher London : Elsevieres_ES
dc.relation386 (9995) 743-800 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAcute Disease/epidemiologyes_ES
dc.subject.meshAdolescentes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAge Distributiones_ES
dc.subject.meshAgedes_ES
dc.subject.meshAged, 80 and overes_ES
dc.subject.meshChildes_ES
dc.subject.meshChild, Preschooles_ES
dc.subject.meshChronic Disease/epidemiologyes_ES
dc.subject.meshCost of Illnesses_ES
dc.subject.meshDeveloped Countries/statistics and numerical dataes_ES
dc.subject.meshDeveloping Countries/statistics and numerical dataes_ES
dc.subject.meshDisabled Persons/statistics and numerical dataes_ES
dc.subject.meshFemalees_ES
dc.subject.meshGlobal Health/statistics and numerical dataes_ES
dc.subject.meshHumanses_ES
dc.subject.meshIncidencees_ES
dc.subject.meshInfantes_ES
dc.subject.meshInfant, Newbornes_ES
dc.subject.meshMalees_ES
dc.subject.meshMiddle Agedes_ES
dc.subject.meshNeglected Diseases/epidemiologyes_ES
dc.subject.meshPrevalencees_ES
dc.subject.meshResidence Characteristics/statistics and numerical dataes_ES
dc.subject.meshSex Distributiones_ES
dc.subject.meshWounds and Injuries/epidemiologyes_ES
dc.subject.meshYoung Adultes_ES
dc.titleGlobal, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013es_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationCollaborators listed at the end of the Articlees_ES
dc.contributor.emailtvos@uw.edues_ES
dc.relation.jnabreviadoLANCETes_ES
dc.relation.journalLancetes_ES
dc.identifier.placeInglaterraes_ES
dc.date.published2015es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1474-547Xes_ES
dc.identifier.doi10.1016/S0140-6736(15)60692-4es_ES
dc.description.monthAgoes_ES
dc.description.abstractotrodiomaBackground—Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013. Methods—Estimates were calculated for disease and injury incidence, prevalence, and YLDs using GBD 2010 methods with some important refinements. Results for incidence of acute disorders and prevalence of chronic disorders are new additions to the analysis. Key improvements include expansion to the cause and sequelae list, updated systematic reviews, use of detailed injury codes, improvements to the Bayesian meta-regression method (DisMod-MR), and use of severity splits for various causes. An index of data representativeness, showing data availability, was calculated for each cause and impairment during three periods globally and at the country level for 2013. In total, 35 620 distinct sources of data were used and documented to calculated estimates for 301 diseases and injuries and 2337 sequelae. The comorbidity simulation provides estimates for the number of sequelae, concurrently, by individuals by country, year, age, and sex. Disability weights were updated with the addition of new population-based survey data from four countries. Findings—Disease and injury were highly prevalent; only a small fraction of individuals had no sequelae. Comorbidity rose substantially with age and in absolute terms from 1990 to 2013. Incidence of acute sequelae were predominantly infectious diseases and short-term injuries, with over 2 billion cases of upper respiratory infections and diarrhoeal disease episodes in 2013, with the notable exception of tooth pain due to permanent caries with more than 200 million incident cases in 2013. Conversely, leading chronic sequelae were largely attributable to noncommunicable diseases, with prevalence estimates for asymptomatic permanent caries and tension-type headache of 2•4 billion and 1•6 billion, respectively. The distribution of the number of sequelae in populations varied widely across regions, with an expected relation between age and disease prevalence. YLDs for both sexes increased from 537•6 million in 1990 to 764•8 million in 2013 due to population growth and ageing, whereas the age-standardised rate decreased little from 114•87 per 1000 people to 110•31 per 1000 people between 1990 and 2013. Leading causes of YLDs included low back pain and major depressive disorder among the top ten causes of YLDs in every country. YLD rates per person, by major cause groups, indicated the main drivers of increases were due to musculoskeletal, mental, and substance use disorders, neurological disorders, and chronic respiratory diseases; however HIV/AIDS was a notable driver of increasing YLDs in sub-Saharan Africa. Also, the proportion of disability-adjusted life years due to YLDs increased globally from 21•1% in 1990 to 31•2% in 2013. Interpretation—Ageing of the world’s population is leading to a substantial increase in the numbers of individuals with sequelae of diseases and injuries. Rates of YLDs are declining much more slowly than mortality rates. The non-fatal dimensions of disease and injury will require more and more attention from health systems. The transition to non-fatal outcomes as the dominant source of burden of disease is occurring rapidly outside of sub-Saharan Africa. Our results can guide future health initiatives through examination of epidemiological trends and a better understanding of variation across countries.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koes_ES


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