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Familial risk across three generations and psychosocial correlates for developing psychopathology in a changing world

dc.creatorCaraveo, Jorge Javier
dc.date.accessioned2017-06-29T03:49:46Z
dc.date.available2017-06-29T03:49:46Z
dc.date.issued2014
dc.identifier2721es_ES
dc.identifier.issn2375-4494es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4570es_ES
dc.identifier.urihttp://dx.doi.org/10.4172/jcalb.1000131es_ES
dc.description.abstractes_ES
dc.description.urihttp://dx.doi.org/10.4172/jcalb.1000131
dc.language.isoenges_ES
dc.publisherOMICS Publishing Groupes_ES
dc.relation2 (2) 1-8 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshes_ES
dc.titleFamilial risk across three generations and psychosocial correlates for developing psychopathology in a changing worldes_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationInstituto Nacional de Psiquiatria “Ramion de la Fuente Muniz”, Direccion de Investigaciones Epidemiológicas y Psicosociales, Calzada Mexico-Xochimilco 101, San Lorenzo Huipulco, Tlalpan, Mexicoes_ES
dc.contributor.emailjjkraveo@gmail.comes_ES
dc.relation.jnabreviadoJ CHILD ADOLESC BEHAVes_ES
dc.relation.journalJournal of Child and Adolescent Behaviores_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2014es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissnes_ES
dc.identifier.doi10.4172/jcalb.1000131es_ES
dc.description.monthes_ES
dc.description.abstractotrodiomaBackground: Human development is a highly complex, environment-dependent process including mental health and psychopathology among its outcomes. Thus, it needs to be studied comprehensively in order to identify correlations and interactions among different biological, economical and psychosocial variables across time and generations. Objective: Is familial psychopathology risk across three generations significantly associated with ongoing psychosocial variables reported by probands? Methods: The study was designed as a household survey on a representative sample of the adult population aged 18 - 65 years in Mexico City. The family-history method was used to obtain information about psychiatric antecedents on their parents and a validated screening instrument was used to evaluate caseness in their offspring. Lifetime prevalence of psychiatric disorders on probands was evaluated using the Composite International Diagnostic Interview. Morbid risk in terms of the odds ratio and prevalence ratio were calculated using logistic regression with fixed effects as well as with generalized estimating equations (GEE) population-averaged models with an exchangeable structure. Aditionally, the population attributable risk percent was also calculated for selected variables associated with the outcome in the complete models. Results: The strenght of the association of familial psychiatric antecedents is moderate between generations on either direction: backwards in regards of proband’s parents or downwards in regards of their children. However, when interaction between the two previous generations was considered, the strenght of the association was higher, crude OR=7.8, and showing significant variations when controlling for the effect of the rest of the variables and especially for probands’ psychosocial correlates. The population attributable risk percent for these variables across generations is sometimes higher than the obtained for familial risk. Conclusions: Findings suggest that besides psychiatric familial risk, socioeconomial and psychodynamic risk factors have been interacting across time and generations contributing to the high prevalence of psychiatric disorders recently reported on youth Mexican population.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koSocioeconomices_ES
dc.subject.koFamily stresses_ES
dc.subject.koPsychopathologyes_ES
dc.subject.koThree generation studyes_ES
dc.subject.koCultural characteristicses_ES
dc.subject.koDiathesis-stresses_ES
dc.subject.koChildhoodes_ES
dc.subject.koAdolescencees_ES
dc.subject.koG x Ees_ES
dc.subject.koCBTD : Cognitive-behavior therapy for depressedes_ES


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