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Event-related functional magnetic resonance images during the perception of phantom limb. A brushing task

dc.creatorPasaye, E.H.
dc.creatorGutiérrez,  R.A.
dc.creatorAlcauter, S.
dc.creatorMercadillo,  R.E.
dc.creatorAguilar-Castañeda,  E.
dc.creatorDe Iturbe, M.
dc.creatorRomero-Romo, J.
dc.creatorBarrios,  F.A.
dc.date.accessioned
dc.date.available
dc.date.issued2010es_ES
dc.identifier2704es_ES
dc.identifier.issn1971-4009es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4553
dc.identifier.urihttps://doi.org/10.1177/197140091002300604es_ES
dc.language.isoenges_ES
dc.publisherBologna : Centauro 2015- : Thousand Oaks, CA : Sage Publicationses_ES
dc.relation23 (6) 665-670 p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.titleEvent-related functional magnetic resonance images during the perception of phantom limb. A brushing taskes_ES
dc.typeartículoes_ES
dc.contributor.affiliationInstitute of Neurobiology, National University of Mexico; Queretaro, Mexicoes_ES
dc.contributor.emailbarrios@inb.unam.mxes_ES
dc.relation.jnabreviadoNEURORADIOL Jes_ES
dc.relation.journalNeuroradiology Journales_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2010es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn2385-1996es_ES
dc.description.monthDices_ES
dc.description.abstractotrodiomaThe phantom limb phenomenon has been used in amputee patients as a paradigm to study plasticity, mainly of the sensorimotor cortex. Nevertheless, most functional studies have been done in upper limb amputee patients using magnetoencephalography and functional magnetic resonance image imaging (fMRI). In addition, the actual experience of phantom limb sensation has not been widely used to study the neural mechanism of the human brain as a conscious knowledge of the phantom limb perception like the integration of the body image in amputee patients. fMRI studies of patients with lower limb amputation have recently been published, but none of these used an event-related design to try to observe only the stimulus application, correlating images with the subject's indication of phantom perception and discarding images with no phantom perception. In this work, we used the event-related fMRI design in two right-handed patients with identical right, transfemoral amputations, performing the same sensitive stimulation in a 3.0 T MR scanner. For comparison, we applied the same paradigm to six control subjects to compare the resulting functional maps. We found areas with statistical significance in the sensorimotor cortex contralateral to the site of stimulation, in the parietal lobe in Brodmann areas 3 in both cases (Patients and Control Subjects), but we also found activation in the Brodmann areas 6, 40, and 5 with stimulation of the stump. We observed a specific activation of the frontoparietal circuit during phantom limb perception in both amputee patients.es_ES
dc.subject.koPhantom limb paines_ES
dc.subject.koPhantom limbes_ES
dc.subject.koEvent related fMRIes_ES


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