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Endomorphin-1, effects on male sexual behavior
dc.creator | Parra-Gámez, Leticia | |
dc.creator | García-Hidalgo, A. Alejandro | |
dc.creator | Salazar-Juárez, A. | |
dc.creator | Antón, B. | |
dc.creator | Paredes, Raúl G. | |
dc.date.accessioned | 2017-06-29T03:47:30Z | |
dc.date.available | 2017-06-29T03:47:30Z | |
dc.date.issued | 2009 | es_ES |
dc.identifier | 2680 | es_ES |
dc.identifier.issn | 0031-9384 | es_ES |
dc.identifier.uri | http://repositorio.inprf.gob.mx/handle/123456789/4529 | |
dc.language.iso | eng | es_ES |
dc.publisher | New York NY. Elsevier Science | es_ES |
dc.relation | 97 (1) 98-101 p. | es_ES |
dc.relation | versión del editor | es_ES |
dc.rights | acceso cerrado | es_ES |
dc.title | Endomorphin-1, effects on male sexual behavior | es_ES |
dc.type | artículo | es_ES |
dc.contributor.affiliation | Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, CP 04510, México | es_ES |
dc.contributor.email | gamezlp@gmail.com | es_ES |
dc.relation.jnabreviado | PHYSIOL BEHAV | es_ES |
dc.relation.journal | Physiology and Behavior | es_ES |
dc.identifier.place | Estados Unidos | es_ES |
dc.date.published | 2009 | es_ES |
dc.identifier.organizacion | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz | es_ES |
dc.identifier.eissn | 1873-507X | es_ES |
dc.identifier.doi | doi:10.1016/j.physbeh.2009.02.004 | es_ES |
dc.description.abstractotrodioma | We examined the effect of endomorphin-1 (EM-1), an endogenous opioid peptide that binds selectively to the μ receptor, on male copulatory behavior in sexually vigorous Wistar rats. In the first experiment, four doses of EM-1 (1, 10, 50, and 100 μM) injected intracerebroventricularly produced a marked increase in ejaculation latency and interintromission interval and reduced the number of ejaculations during the test. In experiment 2 the effects of EM-1 were completely blocked by pretreatment with naloxone (5 mg-kg) 30 min prior to intracerebroventricular injection of EM-1 (100 μM). Collectively these results indicate that the activation of μ receptors by EM-1 modifies parameters associated with ejaculation (increases ejaculation latency and reduces the number of ejaculations) confirming that opioids are released during sexual behavior. | es_ES |
dc.subject.ko | Endomorphin-1 | es_ES |
dc.subject.ko | Opioid receptors | es_ES |
dc.subject.ko | Sexual behavior | es_ES |
dc.subject.ko | Rat | es_ES |
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