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Early Cannabis Use and Estimated Risk of Later Onset of Depression Spells: Epidemiologic Evidence From the Population-based World Health Organization World Mental Health Survey Initiative

dc.creatorDe Graaf, Ron
dc.creatorRadovanovic, Mirjana
dc.creatorvan Laar, Margriet
dc.creatorFairman, Brian
dc.creatorDegenhardt, Louisa
dc.creatorAguilar-Gaxiola, Sergio
dc.creatorBruffaerts, Ronny
dc.creatorde Girolamo, Giovanni
dc.creatorFayyad, John
dc.creatorGureje, Oye
dc.creatorMaria Haro, María
dc.creatorHuang , Yueqin
dc.creatorKostychenko, Stanislav
dc.creatorLépine, Jean-Pierre
dc.creatorMatschinger, Herbert
dc.creatorMedina Mora, Maria Elena
dc.creatorNeumark , Yehuda
dc.creatorOrmel, Johan
dc.creatorPosada-Villa, Jose
dc.creatorStein, Dan J.
dc.creatorTachimori, Hisateru
dc.creatorWells, J. Elisabeth
dc.creatorAnthony, James C.
dc.date.accessioned2017-06-29T03:46:06Z
dc.date.available2017-06-29T03:46:06Z
dc.date.issued2010es_ES
dc.identifier2654es_ES
dc.identifier.issn0002-9262es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4503
dc.identifier.urihttps://doi.org/10.1093/aje/kwq096es_ES
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915487/es_ES
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisherCary, NC : Oxford University Presses_ES
dc.relation172(2) 149-159p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdolescentes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAge Factorses_ES
dc.subject.meshCannabis/adverse effectses_ES
dc.subject.meshCross-Sectional Studieses_ES
dc.subject.meshDepression/epidemiologyes_ES
dc.subject.meshDepression/etiologyes_ES
dc.subject.meshFemalees_ES
dc.subject.meshGlobal Healthes_ES
dc.subject.meshHumanses_ES
dc.subject.meshMalees_ES
dc.subject.meshMental Disorders/complicationses_ES
dc.subject.meshSex Factorses_ES
dc.subject.meshSmoking/adverse effectses_ES
dc.subject.meshWorld Health Organizationes_ES
dc.titleEarly Cannabis Use and Estimated Risk of Later Onset of Depression Spells: Epidemiologic Evidence From the Population-based World Health Organization World Mental Health Survey Initiativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationNetherlands Institute of Mental Health and Addictiones_ES
dc.contributor.emailrgraaf@trimbos.nles_ES
dc.relation.jnabreviadoAM J EPIDEMIOLes_ES
dc.relation.journalAmerican Journal of Epidemiologyes_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2010es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1476-6256es_ES
dc.identifier.doi10.1093/aje/kwq096es_ES
dc.description.monthJules_ES
dc.description.abstractotrodiomaEarly-onset cannabis use is widespread in many countries and might cause later onset of depression. Sound epidemiologic data across countries are missing. The authors estimated the suspected causal association that links early-onset (age <17 years) cannabis use with later-onset (age ≥17 years) risk of a depression spell, using data on 85,088 subjects from 17 countries participating in the population-based World Health Organization World Mental Health Survey Initiative (2001–2005). In all surveys, multistage household probability samples were evaluated with a fully structured diagnostic interview for assessment of psychiatric conditions. The association between early-onset cannabis use and later risk of a depression spell was studied using conditional logistic regression with local area matching of cases and controls, controlling for sex, age, tobacco use, and other mental health problems. The overall association was modest (controlled for sex and age, risk ratio = 1.5, 95% confidence interval: 1.4, 1.7), was statistically robust in 5 countries, and showed no sex difference. The association did not change appreciably with statistical adjustment for mental health problems, except for childhood conduct problems, which reduced the association to nonsignificance. This study did not allow differentiation of levels of cannabis use; this issue deserves consideration in future research.es_ES
dc.subject.koCannabises_ES
dc.subject.koDepressiones_ES
dc.subject.koMental healthes_ES
dc.subject.koWorld healthes_ES


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